PLoS ONE
Articles in this Issue
DArTSNP based genetic diversity analyses in cassava (Manihote esculenta [Cranz]) genotypes sourced from different regions revealed high level of diversity within population
Understanding the extent of genetic diversity is a pre-requisite in cassava breeding program due to its available broad genetic base of the crop and have great opportunity for its genetic improvement....
MCount: An automated colony counting tool for high-throughput microbiology
Accurate colony counting is crucial for assessing microbial growth in high-throughput workflows. However, existing automated counting solutions struggle with the issue of merged colonies, a common occ...
Evidence for infectious merozoites of Plasmodium falciparum from natural isolates of cultured hepatoma cells infected with sporozoites
Previous cell culture systems using various human hepatoma cell lines established that the intra-hepatic stages of Plasmodium falciparum could be studied ex vivo. However, only one of these culture sy...
Development and evaluation of a Physiotherapy-led, WHO-ICOPE-Based, Person-Centered Integrated Care Program (PTICOPE) module to enhance intrinsic capacity in older adults: Protocol for a randomized controlled trial
Background Declining intrinsic capacity (IC), encompassing domains such as locomotion, cognitive function, vitality, vision, hearing, and psychological well-being, is prevalent among older adults, imp...
Emergency admission, previous delirium tremens and increased liver stiffness as risk factors for severe alcohol withdrawal – A prospective study
Objective To determine if increased liver stiffness (ILS) is a risk factor for patients with alcohol withdrawal to develop severe alcohol withdrawal symptoms (SAWS) like delirium tremens (DT) or with...
Incremental and transformational climate change adaptation factors in agriculture worldwide: A comparative analysis using natural language processing
Climate change is projected to adversely affect agriculture worldwide. This requires farmers to adapt incrementally already early in the twenty-first century, and to pursue transformational adaptation...
Leveraging a digital network of pharmacy professionals to test a technology-assisted model to improve pharmacy access to quality-assured COVID-19 rapid antigen tests approved for self-use in Vietnam
Expanding access to rapid and self-use diagnostics in low-and-middle-income countries (LMICs) is crucial for advancing universal health coverage and creating more self-care opportunities. This study a...
An assessment model of bio-efficiency for container terminals in the presence of air emissions
Atmospheric pollutants from container terminal operations have adverse effects on the environment in port regions, leading to increased health risks, including respiratory and cardiovascular diseases...
Wind farm noise negatively impacts the calling behavior of three frogs in Caatinga dry forests
Acoustic signals play a fundamental role in the lives of anurans. With the increasing prevalence of wind farms in Caatinga ecosystems, our goal was to assess whether the noise generated by this energy...
Number of ICD-10 diagnosis fields required to capture sepsis in administrative data and truncation bias: A nationwide prospective registry study
Background In observational studies that use administrative data, it is essential to report technical details such as the number of International Classification of Disease (ICD) co...
Tolerance of Placozoa for temperate climates: Evidence for known and new placozoan clades in the southern waters of Australia
Placozoans are small multicellular sea-dwelling animals that are typically found in shallow, warm ocean waters and have been reported in various marine environments worldwide. Their unique morphology...
Understanding climate-sensitive diseases in Bangladesh using systematic review and government data repository
Background Understanding the effects of climate change on health outcomes is crucial for effective policy formulation and intervention strategies. However, in Low- and Middle-Income Countries, like B...
Correction: Computational evaluation of efflux pump homologues and lignans as potent inhibitors against multidrug-resistant Salmonella typhi
Bioavailability of zinc from different organic zinc chelates and their effect on the growth, whole body, tissue zinc content, enzymes activity and proximate composition of L. rohita
Minerals play an essential role in aquatic animals to maintain their normal physiological and metabolic functions. This feeding trial assessed the impact of various zinc sources on L. rohita performan...
Inter-rater reliability of stress signatures in exfoliated primary dentition - Improving scientific rigor and reproducibility in histological data collection
Accentuated Lines (ALs) in tooth enamel can reflect metabolic disruptions from physiological or psychological stresses during development. They can therefore serve as a retrospective biomarker of gene...
Impact of drill bit wear on temperature increase in dental implant osteotomy: an in vitro study
Objectives Dental implant surgery relies extensively on bone drilling, a critical procedure with intrinsic challenges. Drill bits show significant wear and are frequently utilized beyond the manufact...
Obstacles to inclusion and threats to civil rights: An integrative review of the social experiences of service dog partners in the United States
Service dogs, trained to assist people with disabilities, are known to impact their human partners’ social experiences. While service dogs can act as a “social bridge,” facilitating greater social con...
Person-centered occupational therapy intervention for the prevention of delirium and improvement in occupational performance in elderly patients admitted to an intensive care unit: A randomized controlled single-blinded trial protocol
Among the deleterious effects caused by hospitalization of elderly patients in intensive care unit (ICU), delirium and impaired performance in occupations are frequent and have long-term negative outc...
Low morphology does not lower success after intrauterine insemination unless inseminating motile sperm count is low
The objective of this study was to determine the relationship between strict morphology as assessed on the initial semen analysis during fertility workup and pregnancy rates after intrauterine insemin...
Modelling the potential impact of climate change on the productivity of soybean in the Nigeria Savannas
A well-calibrated and evaluated GROPGRO module of the Decision Support System for Agro-technological Transfer (DSSAT) was used to simulate productivity of soybean in northern Nigeria under climate cha...
Liver transplantation for NASH-related hepatocellular carcinoma versus non-NASH etiologies of hepatocellular carcinoma: A systematic review and meta-analysis
Background Non-alcoholic steatohepatitis (NASH)-associated hepatocellular carcinoma (HCC) has been emerging a predominant reason for liver transplantation (LT). The complexity of comorbidities in thi...
A framework to identify opportunities to address socioscientific issues in the elementary school curricula: A case study from England, Italy, and Portugal
Scientific literacy is crucial to address important and complex societal problems, both current and future. Teaching using a socioscientific issues (SSI) approach is a potential strategy to develop st...
Epidemiological dynamics of dengue in Peru: Temporal and spatial drivers between 2000 and 2022
Dengue, a vector-borne disease driven by climate change, urbanization, and the adaptation of its vector, Aedes aegypti, poses a significant public health challenge. This study analyzed 23 years (2000–...
Vibrational exercise for Crohn’s to observe response (VECTOR): Protocol for a randomized controlled trial
Crohn’s disease (CD) is a long-term inflammatory gastrointestinal disorder, often adversely affecting physical, emotional, and psychological well-being. Pharmaceutical management is habitually adopted...
Evaluating and implementing machine learning models for personalised mobile health app recommendations
This paper focuses on the evaluation and recommendation of healthcare applications in the mHealth field. The increase in the use of health applications, supported by an expanding mHealth market, highl...