PLoS ONE
Articles in this Issue
Trafficking of the telomerase RNA using a novel genetic approach
Telomeres are specialized nucleoprotein structures situated at eukaryotic chromosome ends, vital for preserving genetic information during cell replication. Telomerase, a holoenzyme composed of telome...
Accuracy of point-of-care nasopharyngeal Interleukin 6 and lung ultrasound in predicting the development of bronchopulmonary dysplasia in preterm infants born before 30 weeks of gestation
Background Bronchopulmonary dysplasia (BPD) is a common cause of morbidity in preterm infants, leading to long-term respiratory complications and risk of neurodevelopmental impairment. Although it has...
Mortality, loss to follow-up and advanced HIV disease following virologic success in West African HIV-2 patients
Background People living with HIV-2 are mainly found in West Africa and their identification and treatment have been impaired by diagnostic challenges and availability of effective antiretroviral trea...
Prevalence and regional disparities of undiagnosed diabetes mellitus in Bangladesh: Results from the Bangladesh Demographic and Health Survey data
Background While undiagnosed diabetes mellitus (DM) presents a substantial global concern, there is a dearth of research examining its prevalence and characteristics specifically within the regional...
Effects of Ionizing Radiation on the Biophysical Properties of Type I Collagen Fibrils
Ionizing radiation is extensively employed in both diagnostic and therapeutic medical practices. The impact of this radiation on collagen, a primary structural protein in humans, remains underexplored...
Correction: Semiparametric modeling for the cardiometabolic risk index and individual risk factors in the older adult population: A novel proposal
Emergence to dominance: Estimating time to dominance of SARS-CoV-2 variants using nonlinear statistical models
Background/Objective : Relative proportion of cases in a multi-strain pandemic like the COVID-19 pandemic provides insight on how fast a newly emergent variant dominates the infect...
Understanding patterns of loneliness in older long-term care users using natural language processing with free text case notes
Loneliness and social isolation are distressing for individuals and predictors of mortality, yet data on their impact on publicly funded long-term care is limited. Using recent advances in natural lan...
Integrating soil and crop metrics with precision agriculture: Pusa N Doctor app for sustainable nitrogen management in maize
Efficient nitrogen (N) management is critical for sustaining high maize yields while minimizing environmental impacts, as conventional practices often lead to N losses, greenhouse gas emissions, and r...
Correction: Metabolite changes during developmental transitions in Adonis amurensis Regel et Radde flowers: Insights from HPLC-MS analysis
Human sensory-like neuron surfaceome analysis
Acral and triggerable pain is a hallmark of diseases involving small nerve fiber impairment, yet the underlying cellular mechanisms remain elusive. A key role is attributed to pain-related proteins lo...
Reduced occludin expression is related to unfavorable tumor phenotype and poor prognosis in many different tumor types: A tissue microarray study on 16,870 tumors
Occludin is a key component of tight junctions. Reduced occludin expression has been linked to cancer progression in individual tumor types, but a comprehensive and standardized analysis across human...
A study on the evolution of original sites of fortifications from the perspective of Historic Urban Landscape: Cases of Paris, Beijing, and Moscow
The Historic Urban Landscape theory underscores the importance of historical stratification processes in shaping the overall value of urban heritage. Building on this perspective, this study examines...
Cranial morphology reveals a lack of phylogenetic signal and rapid adaptive radiation in the bat genus Molossus (Chiroptera: Molossidae)
The 16 species of Molossus (Chiroptera: Molossidae) are distributed throughout the Neotropical region and can be classified into two groups: one consisting of morphologically similar yet phylogenetica...
Correction: Creating a diagnostic assessment model for autism spectrum disorder by differentiating lexicogrammatical choices through machine learning
A qPCR assay for the detection of Phytophthora abietivora, an emerging pathogen on fir species cultivated as Christmas trees
Emerging species of the Phytophthora genus are among the most important threats to global plant biodiversity, horticulture and trade. For instance, Phytophthora root rot (PRR) of Christmas trees, main...
Improvements in health-related quality of life are maintained long-term in patients prescribed medicinal cannabis in Australia: The QUEST Initiative 12-month follow-up observational study
Aims Since 2016, more than one million new patients with chronic health conditions have been prescribed medicinal cannabis in Australia. We aimed to assess overall health-related quality of life (HRQ...
PM2.5 from automobile exhaust induces apoptosis in male rat germ cells via the ROS-UPR mt signaling pathway
Objective To explore the underlying mechanism behind the fine particulate matter’s (PM2.5)-mediated regulation of reproductive function in male rats, and to determine the role of vitamins in this proc...
“You take care of people, people will take care of you”: Moral Economies and an Unpredictable Drug Market
Introduction Fentanyl is the leading cause of opioid-related overdose deaths in the United States. Given the exogenous market shock of fentanyl and subsequent transition in the illicit opioid supply,...
Exploring the physical, mental, and social dimensions of middle-aged adults for active and healthy aging: A cross-sectional study
Introduction Population ageing presents a significant global challenge, necessitating sustained efforts to promote active and healthy ageing throughout life to improve quality of life in later years....
Correction: Preterm birth and neonatal mortality in selected slums in and around Dhaka City of Bangladesh: A cohort study
Correction: Evaluating the impact of added greenery on perceived factors of an urban environment in virtual reality
Correction: Classification of Alzheimer disease using DenseNet-201 based on deep transfer learning technique
A new metoposaurid (Temnospondyli) bonebed from the lower Popo Agie Formation (Carnian, Triassic) and an assessment of skeletal sorting
Metoposaurid-dominated bonebeds are relatively commonplace in Upper Triassic continental deposits with at least ten monodominant, densely-packed bonebeds globally. The biostratinomy of several classic...
ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients
Background ABO blood group has been implicated both in susceptibility to, and severity of, SARS-CoV-2 infection. The aim of this study was to explore a potential association between ABO blood group an...