PLoS ONE
Articles in this Issue
Exploring emotion recognition in patients with mild cognitive impairment and Alzheimer’s dementia undergoing a rehabilitation program
Aim This study aimed to explore differences in the emotions of patients with mild cognitive impairment (MCI) and Alzheimer’s dementia (AD) in group rehabilitation using facial anal...
Cynicism among medical students: An in-depth analysis of mental health dynamics and protective factors in medical education using structural equation modeling
Background Medical students frequently grapple with challenges during their studies, including emotional impacts, career socialization, psychiatric comorbidities, and burnout syndrome. Burnout syndrom...
A simple and low-cost electrode based on Nafion-stabilized silver nanoparticles supported on FTO for the electrochemical determination of Pb (II) and Cu (II)
Increasing awareness of the environmental risks posed by heavy metal accumulation in the environment—due to their toxicity and persistence in biological systems—has driven the development of more effi...
Determinants of pelvic organ prolapse among adult gynecologic patients in Mekelle University Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: Case control study design
Background Pelvic organ prolapse is a major cause of morbidity among women in both high-income and low-income countries. Despite the severity of the problem, the risk factors associated with pelvic or...
Core collection construction and genetic diversity analysis of tea plant (Camellia sinensis [L:] O. Kuntze) accessions in Huangshan city using SSR markers
Assessing genetic diversity and building a core collection is essential to advancing tea plant breeding. In this study, ten SSR markers exhibiting robust amplification and polymorphism were employed t...
Determinants of successful driving rehabilitation training in licensed individuals with disabilities
Previous studies have provided that self-driving can enhance the mobility of people with disabilities and their quality of life. The National Rehabilitation Center has been providing driving rehabilit...
Integrating machine learning and neural networks for new diagnostic approaches to idiopathic pulmonary fibrosis and immune infiltration research
Background Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease with a fatal outcome, known for its rapid progression and unpredictable clinical course. However, the tools available for...
Genetic diversity and verification of plant material compliance of Cocoa (Theobroma cacao L.) in the Barombi-Kang Regional variety trial
Cocoa (Theobroma cacao L.) is a pivotal agricultural commodity in Cameroon, which ranks as one of the top five global cocoa producers. This study focused on evaluating the genetic diversity and verify...
RETRACTED: N-Beats architecture for explainable forecasting of multi-dimensional poultry data
The agricultural economy heavily relies on poultry production, making accurate forecasting of poultry data crucial for optimizing revenue, streamlining resource utilization, and maximizing productivit...
Development of a size-separation technique to isolate Caenorhabditis elegans embryos using mesh filters
The free-living nematode Caenorhabditis elegans has been routinely used to study gene functions, genetic interactions, and conserved signaling pathways. Most experiments require that the animals are s...
Imaging-based assessment of muscles and malnutrition predict prognosis in patients with primary hepatocellular carcinoma
Background The significance of imaging-based assessment of muscles and malnutrition in patients with primary hepatocellular carcinoma (HCC) remains unclear. This study aimed to elucidate the prognosti...
Correction: In vivo treatment with a non-aromatizable androgen rapidly alters the ovarian transcriptome of previtellogenic secondary growth coho salmon (Onchorhynchus kisutch)
Genomic insights into the taxonomic status and bioactive gene cluster profiling of Bacillus velezensis RVMD2 isolated from desert rock varnish in Ma’an, Jordan
Extreme environments like arid and semi-arid deserts harbor unique microbial diversity, offering rich sources of specialized microbial metabolites. This study explores Bacillus velezensis RVMD2, a str...
Sustainability of evidence-based policy engagement model: A case study of Advance Family Planning initiative in India
Background Advance Family Planning (AFP) is a global engagement initiative to expand access to quality contraceptive information, services and supplies by fostering policy pledge and investment. Since...
Changes of upper ocean disturbance caused by tropical cyclones in the Western North Pacific main development region (1993–2021)
During the passage of tropical cyclones (TCs) cause severe disturbances in the upper ocean, especially the TC main development region (MDR) (5°-23°N, 127°-160°E) in the Western North Pacific. The main...
The potential effectiveness of probiotics in reducing multiple sclerosis progression in preclinical and clinical studies: A worldwide systematic review and meta-analysis
Background and objective Multiple Sclerosis (MS) is an immune-mediated disease characterized by nerve cell inflammation and demyelination. The effectiveness of probiotics in reducing inflammatory dama...
From blender to farm: Transforming controlled environment agriculture with synthetic data and SwinUNet for precision crop monitoring
The aim of this study was to train a Vision Transformer (ViT) model for semantic segmentation to differentiate between ripe and unripe strawberries using synthetic data to avoid challenges with conven...
Safety of lifitegrast: A real-world pharmacovigilance study based on FAERS
To comprehensively assess the safety of Lifitegrast, a drug for dry eye disease, we conducted a comprehensive analysis of adverse event (AE) reports from the FDA Adverse Event Reporting System (FAERS)...
Regulating the glucose-6-phosphate dehydrogenase encoding gene gsdA and its impact on growth and citric acid production in Aspergillus niger
Glycolysis in A. niger, a key organism in industrial biotechnology, provides essential precursors for efficient citric acid production. Glucose-6-phosphate dehydrogenase (G6PD), encoded by the gene gs...
Psychological safety and patient safety: A systematic and narrative review
Objectives Various psychological concepts have been proposed over time as potential solutions to improving patient safety and quality of care. Psychological safety has been identified as a crucial mec...
Molecular cloning and functional verification of chalcone synthase genes from cassava (Manihot esculenta Crantz) in defense against Tetranychus cinnabarinus infestation
Secondary metabolites such as flavonoids play an important role in protecting plants from biological agents such as fungi, pathogens, bacteria and pests. Chalcone synthase (CHS) is the first enzyme in...
WeNet-RF: An Automatic Classification Model for Financial Reimbursement Budget Items
Accurate classification of budget items is a critical component of financial reimbursement, as it determines the legitimacy and regulatory compliance of financial expenditures. Currently, manual class...
Recognizing employees’ contribution to effectiveness and values: A randomized waitlist-controlled trial of operant-based leadership training
To develop and sustain a healthy and efficient work environment, managers need to provide their employees with relevant and useful performance feedback. However, research on leadership training in fun...
Incidence, associated factors and impact of the post-COVID-19 condition in Brazil: Study protocol of an observational cohort during the Omicron phase
The novel coronavirus (SARS-CoV-2) has caused a significant impact in Brazil, with over 37 million cases and 690,000 deaths. Survivors often experience prolonged symptoms, termed post-COVID-19 conditi...
Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy
The blood-testis barrier (BTB) is composed of tight junctions (TJ) between adjacent Sertoli cells (SCs) and is crucial for sperm growth and development. Aging-induced TJ impairment is closely related...