PLoS ONE

Vol. 20, Issue 6 Issue 6 2025
1950
Articles

Articles in this Issue

Failure probability and location identification of damaged insulators using normal function and monitored leakage current

Moein Monemi, Seyed Mohammad Shahrtash, Mohsen Kalantar Jun 11, 2025 pp. e0314708 10.1371/journal.pone.0314708

The main task of insulators is to isolate the conductor from the tower. These insulators must be able to isolate the high voltages of the transmission lines from the tower without having a leakage cur...

Saturation kinetics and specificity of transporters for L-arginine and asymmetric dimethylarginine (ADMA) at the blood-brain and blood-CSF barriers

Mehmet Fidanboylu, Sarah Ann Thomas Jun 11, 2025 pp. e0320034 10.1371/journal.pone.0320034

Nitric oxide synthases (NOS) synthesize nitric oxide (NO) from L-arginine in endothelial and neuronal cells. Asymmetric dimethylarginine (ADMA) is a homologue of arginine and an endogenous inhibitor o...

Improving lung cancer diagnosis and survival prediction with deep learning and CT imaging

Xiawei Wang, James Sharpnack, Thomas C.M. Lee Jun 11, 2025 pp. e0323174 10.1371/journal.pone.0323174

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients’ survival outcomes. In this paper, we propose to employ convolutional neural...

Longitudinal effect of HCV cure on markers of kidney disease

Javier Cepeda, Mohamed Atta, Katie Zook et al. Jun 11, 2025 pp. e0325699 10.1371/journal.pone.0325699

Chronic hepatitis C infection has been linked to chronic kidney disease. Despite availability of all oral highly curative direct acting antiviral treatment for more than a decade, impact of HCV cure o...

Pesticides and neurodevelopment of children in low and middle-income countries: A systematic review

Bailey Coleman, Iqra Asad, Yi Yan Heng et al. Jun 11, 2025 pp. e0324375 10.1371/journal.pone.0324375

Background Pesticides are increasingly common in low- and middle-income countries (LMICs), where weaker regulations and multiple risk factors for poor neurodevelopment exist. Due to biological and beh...

Global burden of knee osteoarthritis from 1990 to 2021: Trends, inequalities, and projections to 2035

Junjie Chen, Xianshuai Chen, Tianshu Wang et al. Jun 11, 2025 pp. e0320115 10.1371/journal.pone.0320115

Introduction To present the global, regional, and national burden of knee osteoarthritis (KOA) and its causative factors, categorized by age, gender, and sociodemographic indices from 1990 to 2021, an...

A novel approach to group decision-making using generalized bipolar neutrosophic sets

Aliya Fahmi, Aziz Khan, Thabet Abdeljawad Jun 11, 2025 pp. e0317746 10.1371/journal.pone.0317746

This study introduces operational laws for Aczél-Alsina aggregation within the framework of generalized bipolar neutrosophic sets (GBNS), tailored for group decision-making scenarios. Novel aggregatio...

Factors that contribute to loss to follow-up in the medium term after initiation of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in Japanese patients

Takaaki Sugisawa, Fumi Gomi, Yuri Harada et al. Jun 11, 2025 pp. e0325963 10.1371/journal.pone.0325963

Purpose To identify time-specific factors associated with loss to follow-up (LTFU) in the early to medium term after initiating anti-vascular endothelial growth factor (VEGF) treatment in patients wit...

Input-output efficiency, productivity dynamics, and determinants in western China’s higher education: A three-stage DEA, global Malmquist index, and Tobit model approach

Rui Guo, Meng Ye Jun 11, 2025 pp. e0325901 10.1371/journal.pone.0325901

Amid rapid globalization and the expansion of the knowledge economy, enhancing input-output efficiency of higher education is essential for regional development and national competitiveness. In resour...

A novel approach combining YOLO and DeepSORT for detecting and counting live fish in natural environments through video

Nguyen Minh Khiem, Tran Van Thanh, Nguyen Hung Dung et al. Jun 11, 2025 pp. e0323547 10.1371/journal.pone.0323547

Applying Artificial Intelligence (AI) to the monitoring of live fish in natural environments represents a promising approach to the sustainable management of aquatic resources. Detecting and counting...

In-depth exploration of software defects and self-admitted technical debt through cutting-edge deep learning techniques

Sajid Ullah, M. Irfan Uddin, Muhammad Adnan et al. Jun 11, 2025 pp. e0324847 10.1371/journal.pone.0324847

Most previous research focuses on finding Self-Admitted Technical Debt (SATD) or detecting bugs alone, rather to addressing the concurrent identification of both issues. These study investigations sol...

RETRACTED: A novel spectral transformation technique based on special functions for improved chest X-ray image classification

Abeer Aljohani Jun 11, 2025 pp. e0325058 10.1371/journal.pone.0325058

Chest X-ray image classification plays an important role in medical diagnostics. Machine learning algorithms enhanced the performance of these classification algorithms by introducing advance techniqu...

Current applications and outcomes of AI-driven adaptive learning systems in physical rehabilitation science education: A scoping review protocol

Oyindolapo O. Komolafe, Jannatul Mustofa, Mark J. Daley et al. Jun 11, 2025 pp. e0325649 10.1371/journal.pone.0325649

Rationale Integrating artificial intelligence (AI) into education has introduced transformative possibilities, particularly through adaptive learning systems. Rehabilitation science education stands t...

Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass

Amartya T. Mitra, Shubham Rathore, Augusta Jester et al. Jun 11, 2025 pp. e0325229 10.1371/journal.pone.0325229

Lenses are vital components of well-functioning eyes and are crafted through the precise arrangement of proteins to achieve transparency and refractive ability. In addition to optical clarity for mini...

Trend and decomposition analysis of factors influencing teenage pregnancy and motherhood in Nigeria, 2003–2018

Mobolaji M. Salawu, Rotimi Felix Afolabi, Ayo Stephen Adebowale et al. Jun 11, 2025 pp. e0325659 10.1371/journal.pone.0325659

Background Nigeria is among the countries with a high burden of Teenage Pregnancy and Motherhood (TPM) in sub-Saharan Africa. The adverse effect of TPM on young girls is enormous and often compromises...

Cloud-edge collaborative data anomaly detection in industrial sensor networks

Tao Yang, Xuefeng Jiang, Wei Li et al. Jun 11, 2025 pp. e0324543 10.1371/journal.pone.0324543

Industrial sensor networks exhibit heterogeneous, federated, large-scale, and intelligent characteristics due to the increasing number of Internet of Things (IoT) devices and different types of sensor...

Ethanol alters mechanosensory habituation in C. elegans by way of the BK potassium channel through a novel mechanism

Nikolas Kokan, Conny Lin, Alvaro Luna et al. Jun 11, 2025 pp. e0315069 10.1371/journal.pone.0315069

In this research, we investigated how alcohol modulates the simplest form of learning, habituation, in Caenorhabditis elegans. We used our high throughput Multi-Worm Tracker to conduct a large scale s...

Machine learning driven biomarker selection for medical diagnosis

Divyagna Bavikadi, Ayushi Agarwal, Shashank Ganta et al. Jun 11, 2025 pp. e0322620 10.1371/journal.pone.0322620

Recent advances in experimental methods have enabled researchers to collect data on thousands of analytes simultaneously. This has led to correlational studies that associated molecular measurements w...

Digital transformation and corporate ESG performance: Research based on a capability-motivation dual framework

Cuicui Huang Jun 11, 2025 pp. e0325295 10.1371/journal.pone.0325295

This study systematically examines the impact mechanism and heterogeneous characteristics of digital transformation (DT) on corporate environmental, social, and governance (ESG) performance, using pan...

Interpretation of ATR-FTIR spectra of dental adhesives throughout simultaneous polymerization and solvent loss

Arwa Almusa, António H. S. Delgado, Anne Margaret Young Jun 11, 2025 pp. e0325692 10.1371/journal.pone.0325692

This study developed new Fourier transform infrared (FTIR) spectroscopy methods to assess effects of drying level on the composition and polymerization kinetics of One‐Step® (OS), OptibondTM Universal...

Reference values of urinary metabolites of organophosphate in healthy Iranian adults

Rosa Haghshenas, Zahra Soleimani, Yosef Farzi et al. Jun 11, 2025 pp. e0325037 10.1371/journal.pone.0325037

Organophosphorus pesticides are widely used in agriculture in Iran; we evaluated exposure to these pesticides among Iranian adults. Pesticide-specific urinary metabolites were used as biomarkers for e...

Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK

Dan G. O’Neill, Lauren J. Prisk, Dave C. Brodbelt et al. Jun 11, 2025 pp. e0324203 10.1371/journal.pone.0324203

Background Acute diarrhoea is a common canine veterinary presentation in the UK. This study aimed to report the incidence, demographic risk factors and clinical management for acute diarrhoea diagnose...

Buca della Iena and Grotta del Capriolo: New chronological, lithic, and faunal analyses of two late Mousterian sites in Central Italy

Jacopo Gennai, Tom Higham, Marco Romboni et al. Jun 11, 2025 pp. e0315876 10.1371/journal.pone.0315876

New radiocarbon, lithic, faunal, and documentary analyses of two sites, Buca della Iena and Grotta del Capriolo, located in Tuscany (Central Italy) and excavated in the late 1960s’, are presented. The...

Corruption distance and equity strategies in cross-border M&As: The moderating roles of political connections

Xiaoyuan Li Jun 11, 2025 pp. e0325968 10.1371/journal.pone.0325968

This study explores the impact of corruption distance between home and the host countries on equity strategies in cross-border mergers and acquisitions (M&As). In addition, this study evaluates th...

LiMMCov: An interactive research tool for efficiently selecting covariance structures in linear mixed models using insights from time series analysis

Perseverence Savieri, Lara Stas, Kurt Barbé Jun 11, 2025 pp. e0325834 10.1371/journal.pone.0325834

The correct specification of covariance structures in linear mixed models (LMMs) is critical for accurate longitudinal data analysis. These data, characterised by repeated measurements on subjects ove...

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Journal Info

Publisher Public Library of Science
ISSN 1932-6203
Subject Health Sciences
Language English
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