PLoS ONE
Articles in this Issue
Evaluation of organotin (IV) dithiocarbamate compounds as potential anti-leukemia agents towards CCRF-CEM (CCL-119) cell line: Cytotoxic, apoptotic, cell cycle and genotoxic study
Acute lymphoblastic leukemia (ALL) is a common cancer affecting children worldwide, and current treatment has adverse effects such as neurotoxicity. To overcome this problem, new organotin (IV) dithio...
Enhancing knowledge of hypertension among general practitioners in Pakistan through a Train-The-Trainer initiative
Background Hypertension (HTN) affects over a billion people worldwide, with most cases in low- and middle-income countries (LMICs) where awareness and control remain low. In Pakistan, general practiti...
Effects of germicidal far-UVC on ozone and particulate matter in a conference room
The application of 222 nm light from KrCl excimer lamps (GUV222 or far-UVC) is a promising approach to reduce the indoor transmission of airborne pathogens, including the SARS-CoV-2 virus. GUV222 inac...
Randomised trial reveals a mismatch between preferences for and hormonal responses to anthropogenic light colour temperatures
Public streetlights are universally used to improve visibility after dark and improve residents’ safety. However, anthropogenic light negatively impacts human health and well-being, biodiversity and e...
Correction: Physician factors affecting patient preferences in selecting a primary care provider: A qualitative research study in Singapore
Pneumococcal vaccination at 65 years and vaccination coverage in at-risk adults: A retrospective population-based study in France
Objectives Age (> 50 years) is a risk factor for pneumococcal disease, but is not an indication for vaccination in France, by contrast to influenza. In 2018, the pneumococcal vaccine coverage rate...
Modulation of sperm function by estrogen and progesterone using in vitro experiments: A systematic review
Background The steroid hormones progesterone (P4) and Estrogen (E2) are essential for reproduction in both male and female mammals. Steroid hormones can alter sperm function in vitro via several mecha...
A novel multi-modal retrieval framework for tracking vehicles using natural language descriptions
Recent advances in multimodal and contrastive learning have significantly enhanced image and video retrieval capabilities. This fusion provides numerous opportunities for multi-dimensional and multi-v...
Comparison and selection of light-emitting diodes (LEDs) for disease assays on plant pathogenic viruses and bacteria in greenhouses
Supplemental lighting in greenhouses has traditionally been dominated by high-pressure sodium (HPS) lights. However, a shift towards light-emitting diode (LED) technology is gaining momentum due to it...
Two refined creep calculation methods of two-way prestressed concrete
With the advancement of engineering technology, prestressed concrete has been increasingly applied in various structures. To accurately and efficiently evaluate the long-term performance of prestresse...
Secure analysis in cognitive satellite-terrestrial networks with untrusted LEO relaying and friendly jamming
This study examines physical layer security in a cognitive satellite-terrestrial network where a ground user (GU) transmits confidential data to a Geostationary Earth Orbit (GEO) satellite via an untr...
A rolling bearing fault diagnosis method based on an improved parallel one-dimensional convolutional neural network
As a critical component of industrial equipment, the fault diagnosis of rolling bearings is essential for reducing unplanned downtime and improving equipment reliability. Existing methods achieve an a...
Barriers to osteopathic manipulative medicine use: A qualitative study of physician attitudes and experiences
Purpose Despite growing recognition of osteopathic manipulative medicine (OMM) as an effective treatment for chronic pain, little is known about the real-world barriers clinicians face when attempting...
The FGFR inhibitor pemigatinib overcomes cancer drug resistance to KRAS G12C inhibitors in mesenchymal lung cancer
KRAS mutations are high prevalence oncogenic drivers for multiple cancers. With the advent of new classes of KRAS inhibitors that are showing meaningful clinical activity, research is now turning to q...
Measuring individual semantic networks: A simulation study
Accurately capturing individual differences in semantic networks is fundamental to advancing our mechanistic understanding of semantic memory. Past empirical attempts to construct individual-level sem...
Correction: The impact of vocabulary assessments on quality of life: Insights from professionals on their application with students with disabilities
Down-regulation of MIR-378A-3P expression associated with inflammation: The effects of restoring its levels
Epigenetics has emerged as a modulator of inflammation-related diseases and changes in miRNA expression have been associated with regional location, inflamed mucosa and disease activity in Crohn´s dis...
Evaluation of acute ocular toxicity after definitive-intent radiation therapy in canine sinonasal tumors
Acute toxicity and survival were documented in dogs undergoing radiotherapy for sinonasal tumors. However, few studies specifically investigated ocular toxicity, resulting in limited data on radiation...
Perceived social support according to the type and number of addictions
Background Addiction is very closely related to social determinants. It can be an outcome of the excessive consumption pushed by society and be protected against by society’s many positive dimensions....
EIM: An effective solution for improving multi-modal large language models
Enabling large language models (LLMs) to have multi-modal capabilities, such as vision-language learning, has become a current research hotspot and the next milestone in LLM development with the adven...
Bananas in the aftermath of La Palma volcanic eruption (Canary Islands, Spain): A study on the nutritional and toxic element composition of post-disaster production
The 2021 Tajogaite eruption on La Palma devastated banana production, a key crop, with a 50% loss (53,000 tons). Concerned about potential contamination from volcanic ash and magma, we investigated th...
Performance of older adults on MTL- BR Battery: ARE There differences in healthy aging? A pilot study
Objectives Characterize and better understand differences that can occur in performing language tasks with advancing age in order to observe if the current norms of MTL-BR Battery obtained with indivi...
Distribution of pharmacy deserts and its association with digital divide and residential redlining across the United States
Background Recent pharmacy closures across the US has increased the number of communities characterized as “pharmacy deserts.” Residential segregation and structural economic disinvestment including t...
Gentrification influences mosquito community composition at neighborhood and county levels in Miami-Dade County, Florida
Gentrification is occurring across urban areas in the United States and poses threats to marginalized and vulnerable communities through displacement, disruption of social networks, and worsening heal...
Advanced MDCT assessment of abdominal aortic wall integrity and morphometry in the Saudi cohort: A single-centre cross-sectional study
Background Accurate reference values for abdominal aortic dimensions and wall thickness are crucial for the early detection and management of vascular diseases, particularly abdominal aortic aneurysms...