PLoS ONE
Articles in this Issue
Efficient multi-station air quality prediction in Delhi with wavelet and optimization-based models
The swift decline in the air quality in South Asian mega cities, especially Delhi, presents significant threats to human health owing to elevated concentrations of particulate matter (PM2.5) resulting...
Epidemiological factors associated with immunological resistance in household contacts exposed to active tuberculosis in South Africa: A logistic regression analysis
Introduction Studying individuals who do not get infected with tuberculosis (TB) despite being persistently exposed to infectious TB may enable us to identify TB protective mechani...
Utilization of borax and its impact on the income and the livelihood of miners and other stakeholders: A case of Uganda
Background Mineral wealth serves as a crucial driver of economic growth and infrastructure development in many countries, including Uganda. Artisanal and Small-Scale Gold Mining (ASGM) plays a signifi...
rcprd: An R package to simplify the extraction and processing of Clinical Practice Research Datalink (CPRD) data, and create analysis-ready datasets
The Clinical Practice Research Datalink (CPRD) is a large and widely used resource of electronic health records from the UK, linking primary care data to hospital data, death registration data, cancer...
Comparison of registered and survey-based modes of HIV transmission in 2021–2023: Cross-sectional study in the Kyrgyz Republic
Background Accurate identification of the mode of transmission (MoT) of HIV is critical for effective prevention. However, stigma associated with behaviors such as injecting drug use (IDU) and sex bet...
HIV knowledge and reported stigma among South Florida health fair participants
Background Florida had the third greatest number of new HIV diagnoses in the United States in 2020. This cross-sectional study aimed to assess HIV education and perceptions among diverse populations i...
The role of ephaptic coupling and gap junctional coupling in modulating the initiation and dynamics of reentrant arrhythmias
Cardiac myocytes synchronize through electrical signaling to contract heart muscles, facilitated by gap junctions (GJs) located in the intercalated disc (ID). GJs provide low-resistance pathways for e...
Characterization of multi-targeted insulin-mimetic antidiabetic peptides using in silico approaches
Diabetes is a metabolic disease that can affect people at any age. Despite being one of the leading causes of death, the treatment of diabetes is extremely difficult. For the treatment of diabetes mel...
The prevalence of neuropathic pain pathophysiology associated with ankle fracture: A study protocol
Chronic pain is prevalent among U.S. military personnel and often accompanied by comorbid behavioral health disorders and other medical conditions that further complicate its management. According to...
Preventing postoperative pulmonary complications by establishing a machine-learning assisted approach (PEPPERMINT): Study protocol for the creation of a risk prediction model
Background Postoperative pulmonary complications (POPC) are common after general anaesthesia and are a major cause of increased morbidity and mortality in surgical patients. However, prevention and tr...
Correction: Non-pharmaceutical interventions for people living with HIV with cognitive impairment: A scoping review
Adolescents’ perspectives on non-pharmacological pain interventions for sickle cell crisis management: A population-based survey
Background & Aims Nigeria has the highest sickle cell disease (SCD) prevalence globally. Research indicates that adolescents often utilize non-pharmacological interventions (NPIs) to cope with rec...
Dynamical variations, impact factors, and prediction of echinoco-ccosis in Xinjiang by ARIMA-Random Forest Hybrid Model
Background Xinjiang is the second largest pastoral areas, and the main arid and semi-arid regions in China. The echinococcosis in Xinjiang has been brought serious challenge and large pressure for the...
Agent-based modeling of macrophage-fibroblast interactions in the immune response to biomaterials
Foreign body reaction (FBR) denotes the reaction to the implantation of a biomaterial into the body. It triggers cascades of responses in the tissue and involves different cell types including, among...
AI-assisted grading and personalized feedback in large political science classes: Results from randomized controlled trials
Grading and providing personalized feedback on short-answer questions is time consuming. Professional incentives often push instructors to rely on multiple-choice assessments instead, reducing opportu...
Correction: High-performance liquid chromatographic method for determination of voriconazole in pure and gel formulation
Effects of water and fertilizer management on soil bacterial communities, enzyme activities, and nutrient availability in greenhouse tomatoes
Irrigation and fertilization strategies have been extensively employed to enhance the growth and yield of greenhouse tomatoes. However, the impacts of divergent fertilizer application patterns on soil...
Editorial Note: Retraction: The perception of Hungarian food by consumer segments according to food purchasing preferences based on primary research results
HEE-SegGAN: A holistically-nested edge enhanced GAN for pulmonary nodule segmentation
Accurate segmentation of pulmonary nodules plays a critical role in monitoring disease progression and enabling early lung cancer screening. However, this task remains challenging due to the complex m...
Evaluating the construct validity and test-retest reliability of the Orthotic Patient-Reported Outcomes–Mobility (OPRO-M) short forms in lower limb orthosis users
Lower limb orthoses (LLOs) are often prescribed to facilitate mobility in individuals with functional impairments. The Orthotic Patient-Reported Outcomes – Mobility (OPRO-M) is a self-report instrumen...
Identifying and describing alcohol-related paediatric emergency department attendances amongst under 16 year olds including time trends, incidence rates, and sociodemographic factors associated with alcohol-related harm
This study used ED attendance data to identify and describe alcohol-related attendances and identify sociodemographic factors associated with risk of alcohol-related harm. Between 2011 and 2022, N = 7...
Glutamate dehydrogenase from Pantoea ananatis: A new bacterial enzyme with dual coenzyme specificity
Glutamate dehydrogenase (GDH) catalyzes the reversible conversion of α-ketoglutarate (α-KG) to L-glutamate (Glu) and plays an important role in linking nitrogen and carbon metabolism. However, little...
Degradation of catecholate, hydroxamate, and carboxylate model siderophores by extracellular enzymes
Siderophores are low-molecular weight biomolecules with a high affinity for ferric iron (FeIII) that can impact plant and microbial growth. Although their formation and biology have been investigated...
A real-world pharmacovigilance analysis of ALK inhibitor-associated pleural and pericardial effusion using the FDA Adverse Events Reporting System (FAERS) database from 2013 to 2024
Introduction The advent of anaplastic lymphoma kinase (ALK) inhibitors has revolutionized the treatment of ALK-rearranged malignancies, establishing these agents as vital components of precision oncol...
Randomized controlled trial of stress management and resiliency training for depression (SMART-D)-pilot study
Objective Major Depressive Disorder (MDD) is characterized by high stress sensitivity and unsatisfactory response rates to standard treatments. Stress and depression share a bidirectional relationship...