Nature Communications
Articles in this Issue
Photoswitchable intein for light control of covalent protein binding and cleavage
Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease
The negligible role of carbon offsetting in corporate climate strategies
Abstract Carbon credits feature prominently in corporate climate strategies and have sparked public debate about their potential to delay companies’ internal decarbonisation. While i...
A neuronal correlate for time interval estimation in the crow’s telencephalon
Abstract Interval timing, the ability to perceive and estimate durations between events, is essential for many animal behaviors. In mammals, it is linked to specific cortical and sub-cortica...
The maximum Tc of conventional superconductors at ambient pressure
Abstract The theoretical maximum critical temperature (T c) for conventional superconductors at ambient pressure remains a fundamental question in condensed matter physics. Throu...
Constructing synthetic nuclear architectures via transcriptional condensates in a DNA protonucleus
Abstract Nuclear biomolecular condensates are essential sub-compartments within the cell nucleus and play key roles in transcription and RNA processing. Bottom-up construction of nuc...
Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility
Abstract Radial spokes (RSs) are conserved multimolecular structures attached to the axonemal microtubule doublets and are essential for the motility control of both cilia and sperm flagella...
Author Correction: Lnc-mg is a long non-coding RNA that promotes myogenesis
Integrated single-cell atlas of human atherosclerotic plaques
Abstract Atherosclerosis, a major cause of cardiovascular diseases, is characterized by the buildup of lipids and chronic inflammation in the arteries, leading to plaque formation an...
BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells
Monatomic glass formation through competing order balance
Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer
Abstract With the approval of the antibody-drug conjugate enfortumab vedotin (EV), NECTIN4 has emerged as a bona fide therapeutic target in urothelial carcinoma (UC). Here, we report the dev...
Vaginal Lactobacillus crispatus in early pregnancy associates with favorable gestational outcomes in a Japanese maternal-neonatal microbiome cohort
Pleistocene terrestrial warming trend in East Asia linked to Antarctic ice sheets growth
Abstract How terrestrial mean annual temperature (MAT) evolved throughout the past 2 million years (Myr) remains elusive, limiting our understanding of the patterns, mechanisms, and impacts...
The kinetics of nsp7-11 polyprotein processing and impact on complexation with nsp16 among human coronaviruses
Abstract In coronavirus (CoV) infection, polyproteins (pp1a/pp1ab) are processed into non-structural proteins (nsps), which largely form the replication/transcription complex (RTC). The poly...
Racial stereotypes bias the neural representation of objects towards perceived weapons
Amazon forest resistance to drought is increased by diversity in hydraulic traits
Abstract The unique biodiversity and vast carbon stocks of the Amazon rainforests are essential to the Earth System but are threatened by future water balance changes. Empirical evidence sug...
Discovery of a selective alpha-kinase 1 inhibitor for the rare genetic disease ROSAH syndrome
Abstract ROSAH (retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache) syndrome is a rare genetic disease caused by variants in alpha-kinase 1 (ALPK1) resulting in dow...
Sub-diurnal asymmetric warming has amplified atmospheric dryness since the 1980s
Abstract Rising atmospheric vapor pressure deficit (VPD)—a measure of atmospheric dryness, defined as the difference between saturated vapor pressure (SVP) and actual vapor pressure (AVP)—ha...
Cannabis impacts female fertility as evidenced by an in vitro investigation and a case-control study
DelGrad: exact event-based gradients for training delays and weights on spiking neuromorphic hardware
Abstract Spiking neural networks (SNNs) inherently rely on the timing of signals for representing and processing information. Augmenting SNNs with trainable transmission delays, alon...
Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes
Abstract Autism is a neurodevelopmental condition associated with altered resting-state brain function. An increased excitation-inhibition ratio is discussed as a pathomechanism but in-vivo...