Nature Communications
Articles in this Issue
SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape
Anthropogenic climate change may reduce global diazotroph diversity
Caudate serotonin signaling during social exchange distinguishes essential tremor and Parkinson’s disease patients
A reconfigurable piezo-ionotropic polymer membrane for sustainable multi-resonance acoustic sensing
Prediction of cellular morphology changes under perturbations with a transcriptome-guided diffusion model
Abstract Investigating cell morphology changes after perturbations using high-throughput image-based profiling is increasingly important for phenotypic drug discovery, including pred...
Activation–retardation in sol–gel reactions for additive manufacturing of transparent poly(methylsilsesquioxane) aerogels
Backscattering in topological edge states despite time-reversal symmetry
Abstract Spin-momentum-locked edge states of quantum spin Hall insulators provide a compelling platform for spintronic applications, owing to their intrinsic protection against backscatterin...
Lattice-matched molecular-anchor design for high-performance perovskite quantum dot light-emitting diodes
Progressive changes in phenotype, transcriptome and proliferation capacity characterise continued maturation and migration of intestinal cDCs in homeostasis
Abstract Conventional dendritic cells (cDCs) are important antigen presenting cells which link innate and adaptive immunity by transferring antigenic information from peripheral organs to T...
Targeting ALDH16A1 mediated thioredoxin lysosomal degradation to enhance ferroptosis susceptibility in SMARCA4-deficient NSCLC
How climate change and deforestation interact in the transformation of the Amazon rainforest
Plants with higher dispersal capabilities follow ‘abundant-centre’ distributions but such patterns remain rare in animals
Abstract The ‘abundant-centre’ hypothesis posits that a species’ abundance is highest at its range centre and declines towards its range edge. Recently, the hypothesis has been much debated,...
Salt-templated transformation of waste plastics into single-atom catalysts for environmental and energy applications
Hyaluronidase-enhanced subcutaneous delivery of bNAbs: a phase 1 randomized controlled clinical trial in HIV-uninfected women
Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging
Abstract Inositol hexakisphosphate (IP6) promotes HIV-1 assembly by stabilizing the immature Gag lattice and becomes enriched within virions, where it is required for mature capsid assembly....
Microbiome data integration via shared dictionary learning
Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis
CLADES: a hybrid NeuralODE-Gillespie approach for unveiling clonal cell fate and differentiation dynamics
Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation
Abstract CRAF (RAF1) is one of three RAF-family kinases that initiate MAP kinase signaling in response to activated RAS and is essential for oncogenic signaling from mutant KRAS. Like BRAF,...
Inverted temperature gradients in gold–palladium antenna-reactor nanoparticles
Abstract In addition to enhanced fields and possible charge transfer, the concentration of photothermal energy at the nanoscale is a central feature of plasmon-driven photochemistry. It is w...
The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration
Near-global spawning strategies of large pelagic fish
Photonic terahertz phased array via selective excitation of nonlinear Pancharatnam-Berry elements
Abstract Phased arrays are crucial in various technologies, such as radar and wireless communications, due to their ability to precisely control and steer electromagnetic waves. This precise...
Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, yet most patients fail to achieve durable responses. To better understand the tumor microenvironment...