Nature Communications
Articles in this Issue
Femtojoule optical Kerr switching with milliwatt-peak-power in silicon-organic hybrid nanocavity
Abstract All-optical Kerr switches enable ultrafast switching speeds, essential for next-generation communication and computing. However, their practical deployment is hindered by th...
Correlated quantum shift vector of particle-hole excitations
Abstract Excitons are a prime example of how electron interactions affect optical response and excitation. For example, electron-hole interactions produce a bound excitonic spectrum....
Arid3b suppresses CD8 + T cell infiltration and function in microsatellite-stable colorectal cancer via Runx3
Abstract Microsatellite-stable/proficient mismatch repair (MSS/pMMR) colorectal cancer (CRC) is characterized by a cold tumor microenvironment, with limited CD8⁺...
Orbital-resolved imaging of coherent femtosecond exciton dynamics in coupled molecules
Abstract Optical excitation and control of excitonic wavepackets in organic molecules is the basis to energy conversion processes. To gain insights into such processes, it is essenti...
Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes
Abstract Polyethylene terephthalate (PET) plastic waste causes serious environmental pollution due to insufficient recycling rates. Enzymatic PET depolymerization offers a sustainabl...
A high dimensionality approach reveals immunopathogenic responses driving severe pediatric acute respiratory distress syndrome
Abstract Mechanisms underlying paediatric acute respiratory distress syndrome (PARDS) remain poorly understood, limiting advances in diagnosis and treatment. To...
Single-parameter programmed thermomechanical actuation via 3D-printed helical director fields in liquid crystal elastomers
Abstract Stimuli-responsive material like liquid crystal elastomers (LCEs) hold great promise for untethered soft machines, yet conventional extrusion-based 3D p...
Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland
Abstract The interleukin-6 (IL-6) inhibitors tocilizumab and sarilumab have been repurposed for COVID-19 treatment. However, discrepancies exist across global and national COVID-19 g...
Chang’e-6 farside anorthosites indicate hemispherically comparable magma ocean solidification
Abstract Ferroan anorthosites (FANs) reflect the nature of the Moon’s crust formed during the late-stage lunar magma ocean (LMO). Remote sensing suggests a hemispheric dichotomy in c...
A Bayesian modelling framework to improve antibody titer estimation applied to RSV dilution series data
Analysis of computational tumor-infiltrating lymphocytes in breast cancer from the results of the TIGER challenge
Abstract Tumor-infiltrating lymphocytes (TILs) is a recognized prognostic biomarker in breast cancer. However, poor interobserver agreement and limited reproduci...
Learning the PTM code through a coarse-to-fine mechanism-aware framework
Abstract Post-translational modifications (PTMs) form a complex combinatorial “code” that orchestrates protein function and cellular signaling. However, deciphering this code by pred...
The effect of nurse care management on multimorbid patients’ hospital utilization: a comparative-controlled trial and an exploratory cohort study
Catalytic and regulatory basis of tRNA t6A modification by the KEOPS complex
Distributed neural codes of the 3D position in the marmoset frontal cortex and hippocampus
Decoupling of Neogene seawater lithium isotopes from uplift-driven weathering
Abstract The 9‰ increase in seawater lithium isotope (δ 7 Li) during the Cenozoic is widely regarded as evidence for upli...
Efficient elastocaloric drive system enabled by constant-torque and work-recovery design
~100% upcycling of chlorinated/fluorinated plastic mixtures to H2 and nanotubes over FeNi/Ni/C by microwave catalysis
Abstract The catalytic upcycling of plastic mixtures into H 2 and carbon nanotubes (CNTs) represents a transformative str...
Realizing irradiation-resistant metallic alloys by immobilizing induced defects
A long-read human pangenome initiative for comprehensive interpretation of nuclear-embedded mitochondrial DNA
Two distinct SWI/SNF complexes direct chromatin-linked transcriptional programs in Toxoplasma
PromoterAtlas: decoding regulatory sequences across Gammaproteobacteria using a transformer model
Abstract Recent advances in deep learning, particularly transformer architectures, have improved computational approaches for biological sequence analysis. Despite these advances, co...