Journal of Clinical Oncology
Articles in this Issue
Impact of guideline-discordant care for muscle-invasive bladder cancer on preventable survival losses: A national counterfactual analysis of 55,873 patients.
e16586 Background: Guideline-discordant care disproportionately affects racial minorities, uninsured, and underinsured pat...
Failure-to-rescue after pancreatectomy for pancreatic cancer in the United States: National Inpatient outcomes, 2018–2023.
e23232 Background: Pancreatectomy for pancreatic cancer carries substantial postoperative morbidity. As operative mortalit...
Appendiceal cancer: Historical trends in histological composition and cause-specific mortality based on SEER database analysis.
e16485 Background: Appendiceal cancers are rare malignancies characterized by marked histologic heterogeneity and diverse...
An emerging disparity in young-onset lung adenocarcinoma: Evidence from a SEER analysis.
e20677 Background: Lung adenocarcinoma (LUAD) incidence in younger adults has received limited attention, and stage-specif...
Impact of mRNA SARS-CoV-2 vaccination on CAR T-cell therapy outcomes in hematologic malignancies: A multi-center real-world analysis.
11001 Background: The clinical landscape of hematologic malignancies has been reshaped by Chimeric Antigen Receptor (CAR)...
Patterns of upper endoscopy use prior to gastric cancer diagnosis among high-risk populations.
11192 Background: Gastric cancer is frequently diagnosed at advanced stages in the United States, contributing to poor sur...
Separating facts from feeds: An evaluation of social media videos on Barrett’s esophagus.
9043 Background: Esophageal cancer is subdivided into two types based on histopathology, squamous cell carcinoma and adeno...
Effect of induction immunochemotherapy before concurrent chemoradiotherapy on outcomes in limited-stage small cell lung cancer.
e20158 Background: Immunotherapy, chemotherapy, and radiotherapy all play significant roles in the management of small cel...
Clinical efficacy and tolerability of the selective RET inhibitor soxataltinib (SY-5007) in advanced <i>RET</i> fusion–positive non–small cell lung cancer (NSCLC): Primary findings from a confirmatory phase III trial.
8639 Background: Oncogenic RET gene fusions represent a clinically validated molecular driver occurring in approximately 1...
10-year molecular landscape of metastatic colorectal cancer in Latin America: Gender and age-specific mutational patterns in a large Colombian cohort (N=2,543).
e15597 Background: Molecular profiling of KRAS , NRAS...
BRIDGe: Barriers to real-world implementation of diagnostic genomics—Quantifying the genomic awareness-access divide in Indian oncology care.
e13604 Background: Uptake and actionability of molecular testing remain suboptimal in low-and-middle-income settings. In t...
Phase II study of frontline gemcitabine, 5-fluorouracil/leucovorin, and cisplatin (GemFLP) in advanced urachal and non-urachal urinary tract adenocarcinoma.
4515 Background: Adenocarcinomas of the urinary tract are rare malignancies with limited prospective data. Outcomes of tri...
Enrollment outcomes after screening in phase 1 oncology clinical trials: Real-world evidence from a NCI-designated cancer center.
e13720 Background: Despite many efforts to increase diversity enrollment in Phase 1 trials (Ph1) significant disparities p...
The association of nutritional factors on disease control and survival in patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M-HNSCC) treated with anti–PD-1 monoclonal antibody.
6053 Background: Anti-PD-1 mAb therapy is standard of care for systemic treatment for R/M-HNSCC. These patients (pts) also...
Social determinants of health and survival outcomes in metastatic breast cancer (MBC): Retrospective analysis from a major Canadian cancer centre.
e13758 Background: Social determines of health (SDOH), including geography and sociodemographic factors influence cancer o...
Meaning-centered psychotherapy versus dignity therapy for spiritual well-being in patients with cancer: A systematic review and meta-analysis.
e24118 Background: Meaning-Centered Psychotherapy (MCP) and Dignity Therapy (DT) are frequently employed psychotherapeutic...
Impact of adjuvant sequential chemoradiotherapy on long-term overall survival in early-stage cervical cancer: Final analysis of the STARS phase III randomized trial.
5527 Background: The STARS trial (NCT00806117) previously demonstrated that adjuvant sequential chemoradiotherapy (SCRT) s...
Impact of ILT4 on lipid metabolism of tumor-associated macrophages to drive immunosuppression and tumor progression in NSCLC.
e20598 Background: Tumor-associated macrophages (TAMs), as the most abundant immune cells in the tumor microenvironment (T...
The impact of adjusting for c-Kit exon 11 mutation status when comparing prognostic models for gastrointestinal stromal tumors for prediction of recurrence.
e23510 Background: There is minimal data comparing the prognostic models (PM) developed to predict recurrence of Gastroint...
Prognostic significance of pretreatment neutrophil-to-lymphocyte ratio in triple-negative breast cancer: A systematic review and meta-analysis.
e13121 Background: Triple-negative breast cancer (TNBC) lacks reliable prognostic biomarkers beyond standard clinical stag...
Trends and disparities in cerebrovascular disease–related mortality in patients with chronic lymphocytic leukemia: A retrospective analysis across two decades.
e18633 Background: Cerebrovascular disease (CVD) is an important cause of morbidity and mortality in patients with chronic...
Health technology agencies' reimbursement decisions for cancer drugs across four high-income countries.
e23037 Background: For people with advanced cancer, alternative endpoints such as progression-free survival (PFS) often co...
Association of gut microbiota and peri-initiation proton pump inhibitor/antibiotic exposure with outcomes of atezolizumab-bevacizumab-carboplatin-paclitaxel regimen in patients with advanced non-squamous NSCLC: Prospective phase II study (K-TAIL-201).
8541 Background: Concomitant medications that alter gut microbiome composition, such as proton pump inhibitors (PPIs) and...
Long-term survival, disparities, and future burden of multiple myeloma: A population-based analysis.
e19562 Background: Multiple myeloma is a chronic blood cancer in which patients often live for many years, yet the risk of...
Informing optimal duration of adjuvant chemotherapy (ACT) in resected stage I-IV colorectal cancer (CRC) based on early circulating tumor DNA (ctDNA) dynamics.
3501 Background: While ACT is recommended by clinical guidelines for patients (pts) with high-risk stage II and stage III...