Journal of Clinical Oncology
Articles in this Issue
Burden of adolescent and young adult lung cancer in South Asia: 1990−2023.
e22596 Background: Lung cancer is the leading cause of cancer mortality worldwide. South Asia, the world’s most populous r...
Prostate cancer screening in Nigeria: Findings from a multi-city community-based PSA testing outreach.
e13597 Background: Prostate cancer is the most frequently diagnosed cancer and the leading cause of malignancy-related mor...
Comparative efficacy and safety of neoadjuvant immunochemotherapy, chemoradiotherapy, and chemotherapy in resectable locally advanced esophageal squamous cell carcinoma: A network meta-analysis of randomized controlled trials.
e16140 Background: Neoadjuvant chemoradiotherapy (NCRT) followed by surgery is currently the standard of care for resectab...
Coping strategies adopted by caregivers of pediatric oncology patients navigating the economic burden of treatment in a tertiary cancer care center: A qualitative thematic analysis.
e22004 Background: Economic distress due to cost of cancer treatment is a significant challenge for patients and caregiver...
A risk stratification schema for patients with non–small cell lung cancer with multiple organ metastases.
11138 Background: The majority of patients with non-small cell lung cancer (NSCLC) will have multiple organ sites of metas...
A clinical prediction score to identify symptomatic patients at high risk for colorectal cancer in South Africa.
1606 Background: Colorectal cancer (CRC) is the third most diagnosed cancer globally with a rising incidence across sub-Sa...
A phase 1 study of CT-01, a dual molecular glue degrader of GSPT1 and NEK7, as monotherapy and in combination with everolimus in patients with hepatocellular carcinoma.
e15108 Background: Targeted protein degradation (TPD) using molecular glues enables pharmacological modulation of previous...
Post-neoadjuvant Prognostic Nutritional Index as a predictor of pathological response and survival in locally advanced rectal cancer.
e15632 Background: The response to neoadjuvant therapy in locally advanced rectal cancer (LARC) may be influenced by tumor...
EA1181: Accuracy of pre-surgery MRI to predict pathologic complete response after taxane, trastuzumab, and pertuzumab (THP) in HER2-positive breast cancer.
603 Background: Accurate prediction of pathologic complete response (pCR) after preoperative therapy for HER2-positive (HE...
Use of immune checkpoint inhibitors in soft tissue sarcoma: A meta-analysis.
e23560 Background: Soft tissue sarcomas (STS) have historically been treated with surgery, radiation, or chemotherapy. Rec...
Non-invasive strategy for gastric cancer detection: Integration of cell-free DNA fragmentomics and protein biomarkers.
4071 Background: Gastric cancer (GC) ranks the fifth most common cancer worldwide. Although gastroscopy is widely acknowle...
Tumor mutational burden by smoking status in small cell lung cancer: Insights from a limited cohort.
e20122 Background: Tumor mutational burden (TMB) is a potential biomarker in small cell lung cancer (SCLC) and is often in...
Coordinated care interventions and time to treatment initiation in a public health system in Brazil.
e13513 Background: Delays in cancer treatment initiation are associated with increased morbidity and mortality. In Brazil,...
Projected burden of lung cancer and tobacco usage among older adults ≥ 65 in the United States: A CDC WONDER forecasting analysis, 1999–2035.
e20083 Background: Lung cancer and tobacco use are closely linked, with smoking responsible for most cases. Evaluating lon...
Efficacy and safety of immune checkpoint inhibitors after platinum-based therapy for refractory or recurrent malignant pleural mesothelioma: A systematic review and meta-analysis.
e20064 Background: Malignant pleural mesothelioma (MPM) remains highly aggressive. While immune checkpoint inhibitors (ICI...
Early symptom signals preceding end-of-life decline in outpatient palliative oncology.
12053 Background: Timely recognition of clinical decline is challenging in palliative oncology. Symptom trajectories that...
Closing the distance and the Specialist Nursing Optimal Placement Tool (SN-OPT): Strategic placement of specialist cancer nurses to achieve resource and geographic equity in Australia.
11082 Background: Cancer workforce planning that enables effective specialist nurse placement is critical for delivering h...
Stage-dependent divergence of immune prognostic signatures in non–small cell lung cancer.
8066 Background: Tumor mutational burden (TMB) and immune activation are widely studied biomarkers in non–small cell lung...
mRNA-based profile to predict platin sensitivity in NSCLC assessed by Nanostring: A translational analysis of the ETOP/EORTC SPLENDOUR trial.
e20555 Background: Platinum-based chemotherapy is a standard treatment for non-small cell lung cancer (NSCLC), yet clinica...
Use of multi-omics biomarkers to predict benefit from immune checkpoint inhibitors in biliary tract cancers: A systematic review and meta-analysis.
e14587 Background: Predictive biomarkers for immune checkpoint inhibitors (ICIs) in biliary tract cancers (BTC) are urgent...
Correlation of PD-L1 expression with tertiary lymphoid structure maturity and immune cell spatial distribution in colorectal cancer.
e15582 Background: PD-L1 expression is a key biomarker for predicting immune checkpoint inhibitor (ICI) efficacy but shows...
Indocyanine green–guided lymphadenectomy in gastrectomy for gastric cancer: A systematic review and meta-analysis.
e16098 Background: Indocyanine green (ICG) near-infrared fluorescence is increasingly used to guide lymphadenectomy during...
Efficacy and safety of deulorlatinib (TGRX-326) in patients with locally advanced or metastatic ALK+ non–small cell lung cancer: A multicenter, open-label, pivotal phase 2 trial.
8638 Background: Treatment options are limited for anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (...
Efficacy and safety analysis of hepatic arterial infusion chemotherapy plus PD-1/PD-L1 antibodies combined with donafenib or bevacizumab in patients with unresectable hepatocellular carcinoma.
e16155 Background: In unresectable hepatocellular carcinoma (uHCC), it is unknown whether donafenib plus hepatic arterial...
A prospective, single-arm, exploratory study on the efficacy and safety of romiplostim N01 for cancer treatment–induced thrombocytopenia in patients with gastrointestinal cancers.
e16346 Background: Cancer Treatment-Induced Thrombocytopenia (CTIT) is a common complication in patients with gastrointest...