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Identification of UDP-dependent glycosyltransferases in the wallflower cardenolide biosynthesis pathway

Journal of Biological Chemistry Owen S. Patrick, Gordon C. Younkin, Rebecca G. Brody et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108565

High-frequency transcription leads to rapid R-loop formation

Journal of Biological Chemistry Bradleigh Palmer, Chun-Ying Lee, Leya Yang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108514

Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer’s disease

Journal of Biological Chemistry Lihua Sun, Jiahui Liu, Menghan Lu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110226

Challenging activity and signaling bias in tachykinin NK1 and NK2 receptors by truncated neuropeptides

Journal of Biological Chemistry Jacob E. Petersen, Artem Pavlovskyi, Jesper J. Madsen et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108522

The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases

Journal of Biological Chemistry Alexander C. Anderson, Bailey J. Schultz, Eric D. Snow et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108531

Seo1p, a high-affinity, plasma membrane transporter of the γ-Glu-met dipeptide in yeasts and fungi

Journal of Biological Chemistry Pratiksha Dubey, Md Shabbir Ahmad, Sunil Laxman et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108539

Setdb1 and Atf7IP form a hetero-trimeric complex that blocks Setdb1 nuclear export

Journal of Biological Chemistry Leena S. Kariapper, Ila A. Marathe, Ashley B. Niesman et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110171

Fluorescent labeling of proteins in vitro and in vivo using encoded peptide tags

Journal of Biological Chemistry Maya de Luis, Shuwa Xu, Kai Zinn Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110229

Extent of N-glycosylation of the metalloproteinase inhibitor and cytokine TIMP-1 determines pancreatic cancer cell proliferation and survival via CD63

Journal of Biological Chemistry Daniel Häußler, Damjan Manevski, Julian Frädrich et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110211

The bacterial chaperone CsgC inhibits functional amyloid CsgA formation by promoting the intrinsically disordered pre-nuclear state

Journal of Biological Chemistry Anthony Balistreri, Divya Kolli, Sanduni Wasana Jayaweera et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110217

A tumor necrosis factor-α–responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7

Journal of Biological Chemistry Sojung Lee, Yin Yee Ho, Suyu Hao et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108568

EML2 and EML4 splice variants regulate microtubule remodeling during neuronal cell differentiation

Journal of Biological Chemistry Venus Marasi, Rozita Adib, Laura O’Regan et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110252

CRISPRi screen uncovers lncRNA regulators of human monocyte growth

Journal of Biological Chemistry Cristina Flores-Arenas, Eric Malekos, Christy Montano et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110204

Selective inhibition of TRPV3 channel by natural rosmarinic acid and its analogs for alleviation of skin lesions through downregulation of NF-κB pathway

Journal of Biological Chemistry Yaxuan Qu, Shilun Mo, Fei Hou et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110267

MitoSNO inhibits mitochondrial hydrogen peroxide generation by α-ketoglutarate dehydrogenase

Journal of Biological Chemistry Olivia Chalifoux, Samantha Sterman, Ben Faerman et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108510

Molecular glue binding behavior of phosphoantigens to alpaca butyrophilins

Journal of Biological Chemistry Chang Liu, Simin Yi, Mengting Zhang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108555

RIPC improves myocardial injury by promoting mitochondrial protection via the PGC-1α/Nrf2 pathway

Journal of Biological Chemistry Zhenzhou Zhao, Zhiwen Zhang, Xuejie Li et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108476

Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver

Journal of Biological Chemistry Sezin Dagdeviren, Megan F. Hoang, Jialu Wang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110214

All intrinsically active Erk1/2 mutants autophosphorylate threonine207/188, a plausible regulator of the TEY motif phosphorylation

Journal of Biological Chemistry Alexey Baskin, Nadine Soudah, Nechama Gilad et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108509

Blockade of the estrogen receptor alpha–pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity

Journal of Biological Chemistry Elizabeth Twum, Malvin Ofosu-Boateng, Daniel O. Nnamani et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110238