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Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD

Journal of Biological Chemistry Aniket Sen, Shilpa Thakur, Priya Rawat et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108556

A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-κB and tumor cell phenotypes

Journal of Biological Chemistry Xiaoxiao Hao, Yuechuan Chen, Divya Sahu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110172

Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions

Journal of Biological Chemistry Alireza Shoari, Mathew A. Coban, Alexandra Hockla et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110258

LncRNA-induced lysosomal localization of NHE1 promotes increased lysosomal pH in macrophages leading to atherosclerosis

Journal of Biological Chemistry Pengcheng Shi, Bo Tang, Wen Xie et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110246

A high-throughput compatible workflow for the biochemical identification and characterization of molecular glues

Journal of Biological Chemistry Ryan Guilbert, Maxime Couturier, Yuanyuan Si et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108526

Ebola virus nucleoprotein interaction with host protein phosphatase-1 regulates its dimerization and capsid formation

Journal of Biological Chemistry Asrar Ahmad, Bersabeh Tigabu, Andrey Ivanov et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108541

In vitro sulfuration of Rhodobacter capsulatus formate dehydrogenase

Journal of Biological Chemistry Benjamin R. Duffus, Benedict J. Elvers, Christian Teutloff et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108511

CpX Hunter web tool allows high-throughput identification of CpG, CpA, CpT, and CpC islands: A case study in Drosophila genome

Journal of Biological Chemistry Martin Bartas, Michal Petrovič, Václav Brázda et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108537

Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB

Journal of Biological Chemistry Genta Ito, Naoko Utsunomiya-Tate Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108549

Phosphorylation of SNX17 impedes activation of Retriever-mediated sorting

Journal of Biological Chemistry Jan Dominik Speidel, Kaikai Yu, Ralph Thomas Böttcher Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110222

Altering the ligand specificity of DectiSomes

Journal of Biological Chemistry Suresh Ambati, Xiaorong Lin, Zachary A. Lewis et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108566

Characterization of a two-component kinase that initiates the bacterial catabolism of hydroxyphenylethanones

Journal of Biological Chemistry Gara N. Dexter, Jason C. Grigg, Michael Zahn et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110210

Crystal structure and mutagenesis of a nucleic acid–binding BRCT domain in human PARP4

Journal of Biological Chemistry Léonie Frigon, John M. Pascal Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110277

In situ detection of activation of CAPN3, a responsible gene product for LGMDR1, in mouse skeletal myotubes

Journal of Biological Chemistry Chihiro Hisatsune, Fumiko Shinkai-Ouchi, Shoji Hata et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108536

Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIα

Journal of Biological Chemistry Stine J. Gauger, Line B. Palmelund, Yongsong Tian et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108543

Biochemical impact of p300-mediated acetylation of replication protein A: Implications for DNA metabolic pathway choice

Journal of Biological Chemistry Onyekachi Ononye, Sneha Surendran, Tripthi Battapadi et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110250

Recently discovered heteromeric enzymes in natural product biosynthesis

Journal of Biological Chemistry Zhongtian Yu, Ikuro Abe Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108516

The nucleocapsid protein of Crimean–Congo hemorrhagic fever virus interacts with eIF4A to promote the translation of viral mRNA in cells

Journal of Biological Chemistry Saima Ali, Songyang Ren, Alexis Agsaoa et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110173

DNA stimulates the deacetylase SIRT6 to mono-ADP-ribosylate proteins with histidine repeats

Journal of Biological Chemistry Nicholas J. Pederson, Katharine L. Diehl Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108532

Extended neoadjuvant dostarlimab provides durable benefit in resectable dMMR solid tumours

Nature Reviews Clinical Oncology Peter Sidaway Jun 01, 2025 DOI: 10.1038/s41571-025-01027-9