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Hodgkin lymphoma: great progress with room for improvement

Nature Reviews Clinical Oncology Paul J. Bröckelmann Jun 01, 2025 DOI: 10.1038/s41571-025-01012-2

WWP1 mediates the ubiquitination and degradation of HIPK3 in bladder cancer cells

Journal of Biological Chemistry Haichao Chen, Xinyu Na, Pengcheng Hu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108528

MORPHEUS-Liver provides a way forward in expanding the immunotherapy options for hepatocellular carcinoma

Nature Reviews Clinical Oncology Bruno Sangro, Josepmaria Argemí Jun 01, 2025 DOI: 10.1038/s41571-025-01009-x

Throwing a spotlight on genomic dark matter: The power and potential of transposon-insertion sequencing

Journal of Biological Chemistry Laura M. Nolan, Mark A. Webber, Alain Filloux Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110231

N-acetyltransferase 10 promotes glioblastoma malignancy via mRNA stabilization of jumonji and AT-rich interaction domain containing 2

Journal of Biological Chemistry Takuto Inoki, Akito Tsuruta, Yoshinori Masakado et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108544

Aggrecan immobilizes to perineuronal nets through hyaluronan-dependent and hyaluronan-independent binding activities

Journal of Biological Chemistry Matthew Y. Otsuka, Leslie B. Essel, Ashis Sinha et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108525

Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay

Journal of Biological Chemistry Makoto Araki, Yukika Kasuya, Kaho Yoshimoto et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108545

Parkin mediates the mitochondrial dysfunction through mRpL18

Journal of Biological Chemistry Xiuxiu Ti, Hui Zuo, Guochun Zhao et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110208

A TATA-box-binding protein binds single-stranded DNA in two modes: To poly(G) tracts and to flexible DNA regions

Journal of Biological Chemistry Kieran Freitag, Melanie Marlow, Joella Joseph et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108552

Derivation of human trophoblast stem cells from placentas at birth

Journal of Biological Chemistry Victoria Karakis, John W. Britt, Mahe Jabeen et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108505

Mechanism and kinetics of turnover inhibitors of nicotinamide N-methyl transferase in vitro and in vivo

Journal of Biological Chemistry Tomas Akerud, Claudia De Fusco, Peter Brandt et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108492

Allosteric communication mechanism in the glucagon receptor

Journal of Biological Chemistry Wijnand J.C. van der Velden, Elizaveta Mukhaleva, Nagarajan Vaidehi Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108530

TOX High-Mobility Group Box Family Member 4 promotes DNA double-strand break repair via nonhomologous end joining

Journal of Biological Chemistry Feifei Wang, Wenli Gui, Mengtao Rong et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110174

Guard cell and whole plant expression of AtTOR improves performance under drought and enhances water use efficiency

Journal of Biological Chemistry Li Liu, Peng Gao, Huajin Sheng et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110220

Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1

Journal of Biological Chemistry Luba Mahbub, Guennadi Kozlov, Caroline Knorn et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110251

Cooperative inhibition in cytochrome P450 between a substrate and an apparent noncompetitive inhibitor

Journal of Biological Chemistry Yu Hirano, Sachiyo Yoneda, Kaori Yasuda et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108513

Microglial TAK1 promotes neurotoxic astrocytes and cognitive impairment in LPS-induced hippocampal neuroinflammation

Journal of Biological Chemistry Xiao Han, Xin Cao, Qianqian Ju et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110225

Hepatic glutamic-oxaloacetic transaminase promotes mitochondrial respiration energized at complex II and alters whole body metabolism

Journal of Biological Chemistry Brian D. Fink, Ritu Som, Adam J. Rauckhorst et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110261

Nick sealing of polβ mismatch insertion products by LIG1 and LIG3α during 8-oxoG bypass leads to mutagenic or error-free base excision repair

Journal of Biological Chemistry Kar Men Lee, Erick Castro, Jacob Ratcliffe et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108540

Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics

Journal of Biological Chemistry Shubham Das, Saikat Das, Amrita Maity et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108550