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Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake

Journal of Biological Chemistry Meng Ding, Yun Zhang, Xiaoting Xu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110213

CRISPR–Cas applications in agriculture and plant research

Nature Reviews Molecular Cell Biology Aytug Tuncel, Changtian Pan, Joshua S. Clem et al. Jun 01, 2025 DOI: 10.1038/s41580-025-00834-3

Alternative splicing categorizes organ development by stage and reveals unique human splicing variants linked to neuromuscular disorders

Journal of Biological Chemistry Chen Li, Fu-xing Gong, Zhigang Yang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108542

NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation

Journal of Biological Chemistry Yingshi Zhou, Zhihuai Deng, Shiyu Xiong et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108551

A new age in structural S-layer biology: Experimental and in silico milestones

Journal of Biological Chemistry Stephanie Grill-Walcher, Christina Schäffer Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110205

Molecular basis for differential PIP2-mediated association between vinculin and its splice isoform metavinculin

Journal of Biological Chemistry Mohammad Ashhar I. Khan, Venkat R. Chirasani, Muzaddid Sarker et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110232

Loss of SLX4IP leads to common fragile site instability and compromises DNA interstrand crosslink repair in vivo

Journal of Biological Chemistry Andreas Ingham, Mukundhan Ramaswami, Ramanagouda Ramangoudr-Bhojappa et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110244

Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics

Journal of Biological Chemistry Zachary S.C.S. Froom, Neal I. Callaghan, Locke Davenport Huyer Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110203

The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis

Journal of Biological Chemistry Xiaowei Wang, Kenan Peng, Yudi Zhao et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110228

Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-α/Wnt/β-catenin pathway in neuronal cells

Journal of Biological Chemistry Alexis Digman, Edward Pajarillo, Sanghoon Kim et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108529

Phosphorylation modulates secondary structure of intrinsically disorder regions in RNA polymerase II

Journal of Biological Chemistry Wei Chen, Tatiana N. Laremore, Neela H. Yennawar et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108533

The neural stem cell gene PAFAH1B1 controls cell cycle progression, DNA integrity, and paclitaxel sensitivity of triple-negative breast cancer cells

Journal of Biological Chemistry Parth R. Majmudar, Ruth A. Keri Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110235

CMP-sialic acid synthetase in Drosophila requires N-glycosylation of a noncanonical site

Journal of Biological Chemistry Boris Novikov, Devon J. Boland, Ilya Mertsalov et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108483

Shaping epithelial tissues by stem cell mechanics in development and cancer

Nature Reviews Molecular Cell Biology Vincent F. Fiore, Jorge Almagro, Elaine Fuchs Jun 01, 2025 DOI: 10.1038/s41580-024-00821-0

Engineering an antimicrobial chimeric endolysin that targets the phytopathogen Pseudomonas syringae pv. actinidiae

Journal of Biological Chemistry Suzanne L. Warring, Hazel M. Sisson, George Randall et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110224

Microenvironmental determinants of endothelial cell heterogeneity

Nature Reviews Molecular Cell Biology Jesus M. Gomez-Salinero, David Redmond, Shahin Rafii Jun 01, 2025 DOI: 10.1038/s41580-024-00825-w

A cobalamin-dependent pathway of choline demethylation from the human gut acetogen Eubacterium limosum

Journal of Biological Chemistry Ruisheng Jiang, Duncan J. Kountz, Liwen Zhang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108524

The roles of mitochondria in global and local intracellular calcium signalling

Nature Reviews Molecular Cell Biology Benjamín Cartes-Saavedra, Arijita Ghosh, György Hajnóczky Jun 01, 2025 DOI: 10.1038/s41580-024-00820-1

Phase separation as a key mechanism in plant development, environmental adaptation, and abiotic stress response

Journal of Biological Chemistry Karina C. Pougy, Bruna A. Brito, Giovanna S. Melo et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108548

A strategy for liver selective NRF2 induction via cytochrome P450-activated prodrugs with low activity in hypoxia

Journal of Biological Chemistry Mei Ying Ng, Thilo Hagen Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108487