Browse Articles

Key amino acids in RNA polymerase and helicase proteins regulate RNA synthesis efficiency in porcine reproductive and respiratory syndrome virus

Journal of Biological Chemistry Hui Li, Riteng Zhang, Honglin Xie et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110247

Fat accumulation in middle-aged male animals

Nature Reviews Molecular Cell Biology Kim Baumann Jun 01, 2025 DOI: 10.1038/s41580-025-00861-0

CaV3.3 T-type calcium channels contribute to carboplatin resistance in retinoblastoma

Journal of Biological Chemistry Sooyun Kim, Chang Sik Cho, Ha Young Jang et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108535

Specific phosphoinositide interaction of Jps1 is a key feature during unconventional secretion in Ustilago maydis

Journal of Biological Chemistry Sanchi Dali, Michèle Schultz, Marian Köster et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110215

Symmetric stimulation of Hsp90 catalyzed ATP hydrolysis through enhanced active site gate dynamics

Journal of Biological Chemistry Breanna Magnan, Thomas Dumont, Suad Rashid et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110262

Fatty acyl-CoA reductase FAR1 is essential for the testicular seminolipid synthesis required for spermatogenesis and male fertility

Journal of Biological Chemistry Ayano Tamazawa, Tatsuro Naganuma, Kento Otsuka et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108538

Antioxidant capacity of the iron–sulfur cluster assembly protein IscU2 is mediated by aspartate metabolism to promote tumor survival

Journal of Biological Chemistry Xunjun Yang, Na Liang, Dandan Liu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110234

Rapid evolution to preserve a conserved function

Nature Reviews Molecular Cell Biology Mia T. Levine Jun 01, 2025 DOI: 10.1038/s41580-025-00848-x

Delayed inactivation of TRPC6 as a determinative characteristic of FSGS-associated variants

Journal of Biological Chemistry Ryo Okada, Reiko Sakaguchi, Tatsuya Komaki et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110256

Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis

Journal of Biological Chemistry Zhuoran Qi, Jie Luo, Wenfeng Liu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108558

The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth

Journal of Biological Chemistry Paul A. Willard, Jacki Kornbluth Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108527

Identification and design principles of far-red–absorbing chlorophyll in the light-harvesting complex

Journal of Biological Chemistry Keisuke Saito, Makiko Kosugi, Linhao Qiu et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108518

MYC controls STING levels to downregulate inflammatory signaling in breast cancer cells upon DNA damage

Journal of Biological Chemistry Renske Linstra, Chantal Stappenbelt, Femke J. Bakker et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108560

Understanding the machinery that reads the genome

Nature Reviews Molecular Cell Biology Carrie Bernecky Jun 01, 2025 DOI: 10.1038/s41580-025-00844-1

Redox response feature and mechanism of Arf1 and their implications for those of Ras and Rho GTPases

Journal of Biological Chemistry Hope Elizabeth Johnson, Emilynn Leigh Banks, Ostin Samuel Ozuna et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110269

Structural and functional insights into the substrate specificity of the pseudouridine monophosphate phosphatase HDHD1A

Journal of Biological Chemistry Suyoung Seo, Minsoo Kim, Sangkee Rhee Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110257

Variations in kinase and effector signaling logic in a bacterial two component signaling network

Journal of Biological Chemistry Danielle Swingle, Leah Epstein, Ramisha Aymon et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108534

Quantification and structure–function analysis of calpain-1 and calpain-2 protease subunit interactions

Journal of Biological Chemistry Ivan Shapovalov, Prawin Rimal, Pitambar Poudel et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110243

The VanS sensor histidine kinase from type-B vancomycin-resistant enterococci recognizes vancomycin directly

Journal of Biological Chemistry Lina J. Maciunas, Photis Rotsides, Elizabeth J. D’Lauro et al. Jun 01, 2025 DOI: 10.1016/j.jbc.2025.110276

Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications

Journal of Biological Chemistry Chloe Azadegan, John Santoro, Johnathan R. Whetstine Jun 01, 2025 DOI: 10.1016/j.jbc.2025.108454