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Discover research articles across all indexed journals

Long term health related quality of life among individuals after COVID 19 recovery in a multicentric community based study

Scientific Reports Shubhanjali Roy, Alveena Malik, Alka Singh et al. Oct 01, 2025 DOI: 10.1038/s41598-025-16082-6

Rapid thrombogenesis prediction in COVID-19 patients using DNN with data labeling

Scientific Reports Joong-Lyul Lee, Haitao Zhao, Mike Tree et al. Oct 01, 2025 DOI: 10.1038/s41598-025-15541-4

PROTAC SERD vepdegestrant outperforms fulvestrant for advanced-stage ER+HER2− breast cancer harbouring acquired ESR1 mutations

Nature Reviews Clinical Oncology Patrick Neven, Sileny N. Han Oct 01, 2025 DOI: 10.1038/s41571-025-01062-6

Detection of cavities in a salt mine with cosmic muons: expected results and first data

Scientific Reports G. Saracino, G. Nyitrai, F. Ambrosino et al. Oct 01, 2025 DOI: 10.1038/s41598-025-11685-5

EMT and cancer: what clinicians should know

Nature Reviews Clinical Oncology Erik W. Thompson, Andrew D. Redfern, Simone Brabletz et al. Oct 01, 2025 DOI: 10.1038/s41571-025-01058-2

Recognizing Egyptian currency for people with visual impairment using deep learning models

Scientific Reports Ahmed M. Ghanem, Hassan A. Youness, Mohamed Wahba et al. Oct 01, 2025 DOI: 10.1038/s41598-025-20646-x

Abstract This study presents a novel real-time Egyptian currency recognition system designed to assist visually impaired individuals in performing financial transactions independently and securely. The system leverages advanced deep learning models—YOLOv8, YOLOv9, and YOLOv10 to achieve high accuracy and low latency in identifying Egyptian banknotes. Evaluated on a comprehensive dataset of 2,000 annotated images, the models incorporate innovations such as context aggregation, GELAN, and NMS-free training to enhance performance. A review of prior systems highlights their limitations, especially concerning regional currencies. YOLOv10 achieved the best performance, with a precision of 0.9678, F1 score of 0.9715, and mAP@0.5 of 0.9934, surpassing both YOLOv8 and YOLOv9. Compared to traditional techniques, this approach offers significant improvements in accuracy and processing speed, providing a scalable and practical solution for accessible AI applications. These contributions promote financial independence and inclusion for visually impaired users, supporting ongoing advances in assistive technology.

The potential use of scout views as an adjunct tool in CT-guided intervention

Scientific Reports Dominic Conroy, Thomas Werncke, Stephan Waldeck et al. Oct 01, 2025 DOI: 10.1038/s41598-025-22040-z

Abstract The objective of this study was to evaluate the use of scout views as an adjunct tool in CT-guided intervention. Therefore, different devices used for interventional procedures were assigned to three different groups and placed onto an Alderson phantom. Different body diameters were simulated by adding PMMA/aluminum plates. Multiple scout views (ap) were acquired using a standard CT-scanner with different scan parameters. The visibility of the devices was semi-quantitatively scored by three readers. The interrater reliability was calculated using the intraclass correlation coefficient (ICC). The detectability of the 11 different interventional devices was calculated depending on tube potential, tube current–time product, and the thickness of the additional tissue equivalent. Statistical significance was evaluated using Wilcoxon signed-rank test (with Pratt modification) and the Mann–Whitney-U test, respectively. The ICC over all measurements for the three readers as well as the ICC for the three different devices groups was regarded excellent (> 0.9). The device detectability was significantly different for the different additional tissue thicknesses as well as for the three device groups. Material detectability over all readers improved with higher doses. Defining a median visibility of 3 (“good”) or 4 (“very good”) as a cut-off value for clinical routine use, we consider a combination of ≥ 80kVp / ≥ 60 mAs or ≥ 90 kVp / ≥ 40 mAs as reasonable scan parameters in normal and overweight patients in our CT setup. In conclusion, CT scout views have a potential use as an additional tool in CT-guided-intervention by enabling fluoroscopy-like planar imaging that may help to visualize dynamic events such as contrast injection or guidewire manipulation.

Patient-reported outcomes and functional recovery after carpal tunnel surgery in a developing health care system: insights from clinical practice

Scientific Reports Moh’d S. Dawod, Mohammad N. Alswerki, Ahmad F. Alelaumi et al. Oct 01, 2025 DOI: 10.1038/s41598-025-16058-6

Therapeutic targeting of mismatch repair-deficient cancers

Nature Reviews Clinical Oncology Paul Johannet, Benoit Rousseau, Carol Aghajanian et al. Oct 01, 2025 DOI: 10.1038/s41571-025-01054-6

Amyloid β-peptide multimer expressed in green algae efficiently inhibits bacteria growth by disrupting cell membrane permeability

Scientific Reports Ying-Ying Hu, Yan-Xia Liu, Sheng-Nan Sun et al. Oct 01, 2025 DOI: 10.1038/s41598-025-16109-y

Emergent Ferromagnetism and Spin Gapless Conductivity in Atomically Thin Co<sub>3</sub>Sn<sub>2</sub>S<sub>2</sub> Nanosheets

Journal of the American Chemical Society Abhinav Pancholi, Pranav Negi, Kartik Samanta et al. Oct 01, 2025 DOI: 10.1021/jacs.5c08223

Finite element analysis of lateral pressure variations in square steel silos considering parametric impacts

Scientific Reports AlHussein Hilal, Abdel Monem Sanad Oct 01, 2025 DOI: 10.1038/s41598-025-20867-0

Abstract This study develops and validates a 3-D finite-element model for lateral pressures in square, flat-bottomed steel silos, challenging the applicability of conventional design methods. The model, using Mohr–Coulomb for wheat and surface-to-surface contact, closely matches observed pressures and demonstrates that slenderness h/a determines the pressure regime: Janssen-type asymptotic profiles in slender silos (h/a ≥ 7.5) change to Rankine-type linear profiles in squat silos (h/a ≤ 1.5). Therefore, using slender-silo formulae for squat designs may lead to inaccurate estimations of base pressures. A parametric study evaluates material influences: lateral pressure is significantly affected by Poisson’s ratio (raising from 0.28 to 0.45 more than doubles base pressure, + 110%) and wall friction µ, while it shows little sensitivity to Young’s modulus and cohesion. These results provide design-oriented recommendations for the safe and cost-effective sizing of silos across various geometries and granular materials.

Perioperative pembrolizumab demonstrates clinical benefit in locally advanced HNSCC

Nature Reviews Clinical Oncology David Killock Oct 01, 2025 DOI: 10.1038/s41571-025-01057-3

Room-Temperature Electrocatalytic Dehydrogenation and Partial Fragmentation of <i>n</i>-Alkanes

Journal of the American Chemical Society Gong Zhang, Lee Fuller, Christine Lucky et al. Oct 01, 2025 DOI: 10.1021/jacs.5c12806

Synergistic effect of cattle bone and rice husk ash on mechanical and microstructural properties of cement mortar

Scientific Reports Bahiru Bewket Mitikie, Teshome Anteneh Wubetie, Walied A. Elsaigh Oct 01, 2025 DOI: 10.1038/s41598-025-15025-5

Well-Defined Cu Precatalysts Indicate Design Rules for Reactivity in Nitrate Electroreduction

Journal of the American Chemical Society Jia Du, Anna Loiudice, Krishna Kumar et al. Oct 01, 2025 DOI: 10.1021/jacs.5c09246

Research on shear fracture behavior of bolt and design method for retractable coupler

Scientific Reports Haoxu Ding, Tao Zhu, Long Yang et al. Oct 01, 2025 DOI: 10.1038/s41598-025-15471-1

Effects of balance-based visual reaction time exercises on cognitive and physical performance in older adults: a randomized controlled trial

Scientific Reports Fatma Kübra Çekok, Bahar Anaforoğlu Oct 01, 2025 DOI: 10.1038/s41598-025-20418-7

Precision Synthesis of Polyrotaxanes Using Cascade Metathesis Polymerization

Journal of the American Chemical Society Jiaqi Han, Seung Eun Choi, Xin Jiang et al. Oct 01, 2025 DOI: 10.1021/jacs.5c09098

The impact of interventions against science disinformation in high school students

Scientific Reports Carlo Martini, Mara Floris, Piero Ronzani et al. Oct 01, 2025 DOI: 10.1038/s41598-025-16565-6