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AbbVie bets on psychedelic drugs in Gilgamesh buy out

Nature Reviews Drug Discovery Asher Mullard Oct 01, 2025 DOI: 10.1038/d41573-025-00149-0

ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts

Journal of Biological Chemistry Laura Jentschel, Anne Blangy, Guillaume Bompard Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110668

Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB₂FGC Complex

Journal of the American Chemical Society Aaron Klausnitzer, Jagdeep Kaur, Tobias Rath et al. Oct 01, 2025 DOI: 10.1021/jacs.5c11923

Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia

Nature Communications Natalia García-San-Martín, Richard AI Bethlehem, Patricia Segura et al. Oct 01, 2025 DOI: 10.1038/s41467-025-63792-6

Improved vascular response to a novel polymeric blend PLLA/PLGA coronary scaffold material: preclinical study

Scientific Reports Piotr P. Buszman, Mateusz Kachel, Karolina Łukasik et al. Oct 01, 2025 DOI: 10.1038/s41598-025-15997-4

Towards a broad-spectrum antiviral agent

Nature Reviews Drug Discovery Sarah Crunkhorn Oct 01, 2025 DOI: 10.1038/d41573-025-00145-4

Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model

Journal of Biological Chemistry Paulina Ormazabal, Camila Gherardelli, Cristina Pinto et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110607

A General Copper-Catalyzed Radical Cross-Coupling of Unactivated Alkyl Halides

Journal of the American Chemical Society Fu-Li Wang, Qian Xie, Xiao-Yu Chen et al. Oct 01, 2025 DOI: 10.1021/jacs.5c10285

Resolving chemical-motif similarity with enhanced atomic structure representations for accurately predicting descriptors at metallic interfaces

Nature Communications Cheng Cai, Tao Wang Oct 01, 2025 DOI: 10.1038/s41467-025-63860-x

Pulegone induced apoptotic and anti-proliferative potential in cervical cancer via P53, BAX and BCL2

Scientific Reports Tahir Maqbool, Faheem Hadi, Sadia Naz et al. Oct 01, 2025 DOI: 10.1038/s41598-025-15963-0

Combination therapy alleviates AD-related pathologies

Nature Reviews Drug Discovery Sarah Crunkhorn Oct 01, 2025 DOI: 10.1038/d41573-025-00146-3

Mapping cellular cytosolic pH in vivo under physiological and pathophysiological conditions

Journal of Biological Chemistry Shuwei Zhang, Xiaoxin Hu, Bowen Zhang et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110637

Scalable solution-processed ferroelectric polymers exhibiting markedly enhanced piezoelectricity

Nature Communications Ze Yuan, Hui Tong, Zekai Fei et al. Oct 01, 2025 DOI: 10.1038/s41467-025-63849-6

Unleashing the synergistic interaction between Meloidogyne enterolobii and Fusarium sp. in guava wilt complex disease

Scientific Reports Shravani, K. C. Kiran Kumar, Raghavendra K. Mesta et al. Oct 01, 2025 DOI: 10.1038/s41598-025-97767-w

Potentiating the integrated stress response

Nature Reviews Drug Discovery Sarah Crunkhorn Oct 01, 2025 DOI: 10.1038/d41573-025-00147-2

Annexin A2 interferes with complement regulation within the glomerulus

Journal of Biological Chemistry Brandon Renner, Jennifer Laskowski, Felix Poppelaars et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110657

Multicyclic Peptides Targeting PD-L1 for Radiotheranostics: From Discovery to Clinical Proof-of-Concept

Journal of the American Chemical Society Xueting Cheng, Shuo Jiang, Xingtong Peng et al. Oct 01, 2025 DOI: 10.1021/jacs.5c11292

Wafer-scale fabrication of memristive passive crossbar circuits for brain-scale neuromorphic computing

Nature Communications Sanghyeon Choi, Sai Sukruth Bezugam, Tinish Bhattacharya et al. Oct 01, 2025 DOI: 10.1038/s41467-025-63831-2

Clinicopathological analysis of GLUT-1, GLS1, and GLS2 expression in breast cancer tissues from Jordanian patients

Scientific Reports Haneen A. Basheer, Ahlam Zaid Alkilani, Samir Al Bashir et al. Oct 01, 2025 DOI: 10.1038/s41598-025-03123-3

Prime editing treats childhood neurological disease

Nature Reviews Drug Discovery Sarah Crunkhorn Oct 01, 2025 DOI: 10.1038/d41573-025-00144-5