Nature Communications

Methionine metabolite spermidine inhibits tumor pyroptosis by enhancing MYO6-mediated endocytosis

Jiawei Wu, Cong Ding, Chuqing Zhang et al. Mar 04, 2025 10.1038/s41467-025-57511-4

A framework for integrating genomics, microbial traits, and ecosystem biogeochemistry

Zhen Li, William J. Riley, Gianna L. Marschmann et al. Mar 04, 2025 10.1038/s41467-025-57386-5

In-situ positive electrode-electrolyte interphase construction enables stable Ah-level Zn-MnO2 batteries

Guojun Lai, Zequan Zhao, Hao Zhang et al. Mar 04, 2025 10.1038/s41467-025-57579-y

Crucial roles of Grr1 in splicing and translation of HAC1 mRNA upon unfolded stress response

Nichika Sato, Yu Nakano, Yasuko Matsuki et al. Mar 04, 2025 10.1038/s41467-025-57360-1

Temporal Contrastive Learning through implicit non-equilibrium memory

Martin J. Falk, Adam T. Strupp, Benjamin Scellier et al. Mar 04, 2025 10.1038/s41467-025-57043-x

Abstract The backpropagation method has enabled transformative uses of neural networks. Alternatively, for energy-based models, local learning methods involving only nearby neurons offer ben...

AAV9-mediated MYBPC3 gene therapy with optimized expression cassette enhances cardiac function and survival in MYBPC3 cardiomyopathy models

Amara Greer-Short, Anna Greenwood, Elena C. Leon et al. Mar 04, 2025 10.1038/s41467-025-57481-7

Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people

Marion Pardons, Laurens Lambrechts, Ytse Noppe et al. Mar 04, 2025 10.1038/s41467-025-57332-5

Safety, immunogenicity and effect on viral rebound of HTI vaccines combined with a TLR7 agonist in early-treated HIV-1 infection: a randomized, placebo-controlled phase 2a trial

Lucia Bailón, José Moltó, Adrian Curran et al. Mar 04, 2025 10.1038/s41467-025-57284-w

LNP-RNA-mediated antigen presentation leverages SARS-CoV-2-specific immunity for cancer treatment

Yonger Xue, Xucheng Hou, Yichen Zhong et al. Mar 04, 2025 10.1038/s41467-025-57149-2

Tailoring asymmetric RuCu dual-atom electrocatalyst toward ammonia synthesis from nitrate

Kaiyuan Liu, Zhiyi Sun, Xingjie Peng et al. Mar 04, 2025 10.1038/s41467-025-57463-9

CTDP1 and RPB7 stabilize Pol II and permit reinitiation

Haonan Zheng, Qiqin Xu, Dexun Ji et al. Mar 04, 2025 10.1038/s41467-025-57513-2

Hot season gets hotter due to rainfall delay over tropical land in a warming climate

Fengfei Song, Hongqiang Dong, Lixin Wu et al. Mar 04, 2025 10.1038/s41467-025-57501-6

Canted antiferromagnetism in a spin-orbit coupled Seff = 3/2 triangular-lattice magnet DyAuGe

Takashi Kurumaji, Masaki Gen, Shunsuke Kitou et al. Mar 04, 2025 10.1038/s41467-025-57318-3

Impact-induced ultra-high melting point oldhamite discovered in Chang’E-6 lunar soil

Chen Li, Yang Li, Ronghua Pang et al. Mar 04, 2025 10.1038/s41467-025-57337-0

Distinct gene regulatory dynamics drive skeletogenic cell fate convergence during vertebrate embryogenesis

Menghan Wang, Ana Di Pietro-Torres, Christian Feregrino et al. Mar 04, 2025 10.1038/s41467-025-57480-8

Abstract Cell type repertoires have expanded extensively in metazoan animals, with some clade-specific cells being crucial to evolutionary success. A prime example are the skeletogen...

Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation

Heng Zhou, Xiaoling He, Yue Xiong et al. Mar 04, 2025 10.1038/s41467-025-57478-2

Microbiome-emitted scents activate olfactory neuron-independent airway-gut-brain axis to promote host growth in Drosophila

Jin-Woo Lee, Kyung-Ah Lee, In-Hwan Jang et al. Mar 04, 2025 10.1038/s41467-025-57484-4

GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization

Dinh Nam Tran, Yeon Jeong Hwang, Keun Cheon Kim et al. Mar 04, 2025 10.1038/s41467-025-57173-2

Prospective cohort study of fatigue before and after SARS-CoV-2 infection in the Netherlands

Anne J. Huiberts, Siméon de Bruijn, Stijn P. Andeweg et al. Mar 04, 2025 10.1038/s41467-025-56994-5

Mechanistic insights into nonlinear effects in copper-catalyzed asymmetric esterification

Xiaotao Zhu, Meirong Huang, Hongli Bao et al. Mar 04, 2025 10.1038/s41467-025-57380-x

Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Junquan Song, Rongyuan Wei, Chenchen Liu et al. Mar 04, 2025 10.1038/s41467-025-57465-7

Determinants of response and molecular dynamics in HER2+ER+ breast cancers from the NA-PHER2 trial receiving HER2-targeted and endocrine therapies

Maurizio Callari, Matteo Dugo, Marco Barreca et al. Mar 04, 2025 10.1038/s41467-025-57293-9

CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate the histone supply

Tae-Kyeong Jeong, R. Ciaran MacKenzie Frater, Jongha Yoon et al. Mar 04, 2025 10.1038/s41467-025-56976-7

PARP inhibitor radiosensitization enhances anti-PD-L1 immunotherapy through stabilizing chemokine mRNA in small cell lung cancer

Xiaozhuo Ran, Bell Xi Wu, Venkatasubramanian Vidhyasagar et al. Mar 04, 2025 10.1038/s41467-025-57257-z

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

Xin Zhang, Chao Yang, Chengle Zhang et al. Mar 04, 2025 10.1038/s41467-025-57445-x

Abstract Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. Here we develop a mouse...

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