Nature Communications

The essential clathrin adapter protein complex-2 is tumor suppressive specifically in vivo

Abstract The microenvironment is a rich source of new cancer targets. We thus used a targeted single-guide RNA library to screen a panel of human pancreatic cancer lines for genes uniquely a...

Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling

Abstract The HIV-1 TAR RNA plays key roles in viral genome architecture, transcription and replication. Previous structural analyses focused on its upper stem loop, which has served as a par...

The influence of subglacial lake discharge on Thwaites Glacier ice-shelf melting and grounding-line retreat

Abstract The retreat of the Antarctic Ice Sheet is conventionally attributed to increased ocean melting of ice shelves, potentially enhanced by internal instability from grounding lines near...

A bioinspired in-materia analog photoelectronic reservoir computing for human action processing

A prenatal window for enhancing spatial resolution of cortical barrel maps

Dynamic multimodal information encryption combining programmable structural coloration and switchable circularly polarized luminescence

Author Correction: Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling

Retention of high-pressure solution-processable metastable phase to ambience via differential sublattice rigidity for broadband photodetectors

Ultrafast unidirectional spin Hall magnetoresistance driven by terahertz light field

Abstract The ultrafast control of magnetisation states in magnetically ordered systems poses significant technological challenges yet is vital for the development of memory devices that oper...

Towards a holistic framework for multimodal LLM in 3D brain CT radiology report generation

Reply to: Validation of blood-based detection of breast cancer highlights importance for cross-population validation

Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer

Abstract ER-positive/HER2-negative (ERpHER2n) breast cancer classified as PAM50 HER2-enriched (ERpHER2n-HER2E) represents a small high-risk patient subgroup. In this study, we investigate ge...

Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance

Tunneling-barrier-controlled sensitive deep ultraviolet photodetectors based on van der Waals heterostructures

Tuning Li occupancy and local structures for advanced Co-free Ni-rich positive electrodes

Abstract Structure evolution and surface reactivity have long been regarded as the most crucial points for studying Ni-rich positive electrodes for Li-ion batteries. Unfortunately, the influ...

Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients

Structural basis for transcription activation through cooperative recruitment of MntR

Author Correction: Evidence for large thermodynamic signatures of in-gap fermionic quasiparticle states in a Kondo insulator

Solvent-regulable interfacial groups enable on-demand superhydrophobic/superhydrophilic silica aerogels

Perovskite spin light-emitting diodes with simultaneously high electroluminescence dissymmetry and high external quantum efficiency

Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice

VITAP: a high precision tool for DNA and RNA viral classification based on meta-omic data

Irreproducible SEBS wrinkling based on spin evaporation enabling identifiable artificial finger pad electronics

Author Correction: Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development

Validation of blood-based detection of breast cancer highlights importance for cross-population validation