Nature Communications
Articles in this Issue
Lineage-dependent variations in single-cell antibiotic susceptibility reveal the selective inheritance of phenotypic resistance in bacteria
An aggregation-induced conformation locking strategy facilitates the activation of lipase biocatalyst
Acidity-driven gas-particle partitioning of nitrate regulates its transport to Arctic through the industrial era
A comparison of intramuscular (Zimhi) and intranasal naloxone (Narcan) in reversal of fentanyl-induced apnea: a randomized, crossover, open-label trial
On-demand, readily degradable Poly-2,3-dihydrofuran enabled by anion-binding catalytic copolymerization
A CRISPR/Cas9-based enhancement of high-throughput single-cell transcriptomics
Abstract Single-cell RNA-seq (scRNAseq) struggles to capture the cellular heterogeneity of transcripts within individual cells due to the prevalence of highly abundant and ubiquitous...
LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels
Abstract Liquid-liquid phase separation (LLPS) phenomenon plays a vital role in multiple cell biology processes, providing a mechanism to concentrate biomolecules and promote cellula...
Polarization-sensitive in-sensor computing in chiral organic integrated 2D p-n heterostructures for mixed-multimodal image processing
Electronic interferometry with ultrashort plasmonic pulses
State-led climate action can cut emissions at near-federal costs but favors different technologies
Chromosome fusions shaped karyotype evolution and evolutionary relationships in the model family Brassicaceae
Abstract The ancestral crucifer karyotype and 22 conserved genomic blocks (CGBs) facilitate phylogenomic analyses in the Brassicaceae. Chromosomal rearrangements reshuffled CGBs of ancestral...
Streaks on martian slopes are dry
A battle against arsenic toxicity by Earth’s earliest complex life forms
Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma
Abstract Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) of the salivary gland are rare tumours that can be difficult to distinguish from each other and other salivary gland tu...
Spin-torque skyrmion resonance in a frustrated magnet
Abstract The frustrated Fe3Sn2 magnet is technologically attractive due to its extreme-temperature skyrmion stability, large topological Hall effect, and current-induced helicity switching a...
Single-cell transcriptomic characterization of microscopic colitis
Abstract Microscopic colitis (MC) is a chronic inflammatory disease of the large intestine and a common cause of chronic diarrhea in older adults. Here, we use single-cell RNA sequencing ana...
Distinctly different active sites of ZnO-ZrO2 catalysts in CO2 and CO hydrogenation to methanol reactions
Abstract The active site of a solid catalyst varies sensitively with the catalyzed reaction. Herein, using experimentally measured elementary surface reaction kinetics of CO2 or CO hydrogena...
A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses
Abstract Factors governing the clinical trajectory of Plasmodium falciparum infection remain an important area of investigation. Here we present transcriptomic, proteomic and metabolomic ana...
Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans
Ultrafast dynamics of electronic friction energy dissipation in defective semiconductor monolayer
A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning
A reduced ability to discriminate social from non-social touch at the circuit level may underlie social avoidance in autism
Abstract Social touch is critical for communication to impart emotions and intentions. However, certain autistic individuals experience aversion to social touch. Here, we used Neuropixels pr...
Auricular malformations are driven by copy number variations in a hierarchical enhancer cluster and a dominant enhancer recapitulates human pathogenesis
Abstract Enhancers, through the combinatorial action of transcription factors (TFs), dictate both the spatial specificity and the levels of gene expression, and their aberrations can result...