An aggregation-induced conformation locking strategy facilitates the activation of lipase biocatalyst

A Anlian Huang (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, GBRCE for Functional Molecular Engineering, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, China) Z Zhi-Wei Li (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, GBRCE for Functional Molecular Engineering, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, China) L Lihong Guo N Ningyi Zhong L Linjing Tong (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry) Y Yanbin Xu X Xiaomin Ma F Fang Zhu (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry) G Guosheng Chen (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry) S Siming Huang (Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital) G Gangfeng Ouyang (School of Chemical Engineering and Technology)

Article Details

Volume / Issue Vol. 16, Issue 1
Published May 19, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (11)

A

Anlian Huang

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, GBRCE for Functional Molecular Engineering, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, China

Z

Zhi-Wei Li

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, GBRCE for Functional Molecular Engineering, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, China

L

Lihong Guo

N

Ningyi Zhong

L

Linjing Tong

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry

Y

Yanbin Xu

X

Xiaomin Ma

F

Fang Zhu

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry

G

Guosheng Chen

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry

S

Siming Huang

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital

G

Gangfeng Ouyang

School of Chemical Engineering and Technology