Nature Communications
Articles in this Issue
High-energy and fast-charging lithium metal batteries enabled by tuning Li+-solvation via electron-withdrawing and lithiophobicity functionality
Reactive oxygen species responsive nanomotors for gene edited metabolic disruption and immunotherapy
Nano-engineered thin-film thermoelectric materials enable practical solid-state refrigeration
Pressure tuning of competing interactions on a honeycomb lattice
Global patterns of rain-on-snow and its impacts on runoff from past to future projections
Single V2 defect in 4H silicon carbide Schottky diode at low temperature
Abstract Nanoelectrical and photonic integration of quantum optical components is crucial for scalable solid-state quantum technologies. Silicon carbide stands out as a material with mature...
Additive manufacturing of carbon fiber-reinforced thermoset composites via in-situ thermal curing
Whole genome sequencing improves tissue-of-origin diagnosis and treatment options for cancer of unknown primary
Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche
Abstract Bone metastasis is a major cause of cancer death; however, the epigenetic determinants driving this process remain elusive. Here, we report that histone methyltransferase ASH1L is g...
CellFM: a large-scale foundation model pre-trained on transcriptomics of 100 million human cells
A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data
Tuning friction force and reducing wear by applying alternating electric current in conductive AFM experiments
Stochastic gene expression in auxin signaling in the floral meristem of Arabidopsis thaliana
Abstract Cells display striking stochasticity in gene expression, which plays an important role in development, disease, and regeneration. Previous studies have found stochastic gene express...
Standardization guidelines and future trends for PET hydrolase research
Impacts of convection, chemistry, and forest clearing on biogenic volatile organic compounds over the Amazon
Abstract The Amazon rainforest is the largest source of biogenic volatile organic compounds (BVOCs) to the atmosphere. To understand the distribution and chemistry of BVOCs, airborne and gro...
Chromogranin A deficiency attenuates tauopathy by altering epinephrine–alpha-adrenergic receptor signaling in PS19 mice
Abstract Metabolic disorders such as insulin resistance and hypertension are potential risk factors for aging and neurodegenerative diseases. These conditions ar...
DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases
SKSR1 identified as key virulence factor in Cryptosporidium by genetic crossing
Iron-catalyzed aliphatic C–H functionalization to construct carbon–carbon bonds
Abstract Although cytochrome P450 enzymes are powerful catalysts for hydrogen-atom abstraction from alkanes by iron-oxo species, the process typically leads to oxygenated products due to ult...
An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration
Human mitochondrial ferritin exhibits highly unusual iron-O2 chemistry distinct from that of cytosolic ferritins
Abstract Ferritins are ubiquitous proteins that function in iron storage/detoxification by catalyzing the oxidation of Fe2+ ions and solubilizing the resulting Fe3+-oxo mineral. Mammalian ti...
Freezing induced incorporation of betaine in lipid nanoparticles enhances mRNA delivery
Multidrug-resistant Shigella flexneri outbreak affecting humans and non-human primates in New Mexico, USA
Evolution of dislocations during the rapid solidification in additive manufacturing
Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
Abstract Cytosine base editors enable programmable and efficient genome editing using an intermediate featuring a U•G mismatch across from a DNA nick. This intermediate facilitates two major...