DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases

R Ruixin Ge M Miao Chen (Department of Chemistry) S Sijin Wu S Sirui Huang P Ping Zhou M Minghui Cao (Department of Pathology, University of California, San Diego, La Jolla, California 92093, United States) F Fan Zhang J Jinzhi Zang Y Yigao Zhu J Jingrui Li G Guilin Ni Z Zhihao Yang Q Qingchao Li (Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University) W Wei Pan L Liang Zhang M Min Liu C Chenghao Xuan H Haiyang Yu J Jun Zhou S Songbo Xie

Article Details

Volume / Issue Vol. 16, Issue 1
Published May 20, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

R

Ruixin Ge

M

Miao Chen

Department of Chemistry

S

Sijin Wu

S

Sirui Huang

P

Ping Zhou

M

Minghui Cao

Department of Pathology, University of California, San Diego, La Jolla, California 92093, United States

F

Fan Zhang

J

Jinzhi Zang

Y

Yigao Zhu

J

Jingrui Li

G

Guilin Ni

Z

Zhihao Yang

Q

Qingchao Li

Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University

W

Wei Pan

L

Liang Zhang

M

Min Liu

C

Chenghao Xuan

H

Haiyang Yu

J

Jun Zhou

S

Songbo Xie