Nature Communications
Articles in this Issue
Enrichment of decidual CD11c + CD8 + T cells with altered immune function in early pregnancy loss
Constitutive inflammation and epithelial-mesenchymal transition dictate sensitivity to nivolumab in CONFIRM: a placebo-controlled, randomised phase III trial
Abstract Leveraging adaptive tumour immunity to control mesothelioma via immune checkpoint blockade is now a standard therapeutic approach. However, the determinants of sensitivity remain el...
In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor
Abstract The Apelin receptor (APLNR), a class A G-protein coupled receptor, plays a crucial role during cardiovascular development and tumor angiogenesis. To understand its spatiotemporal ac...
Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI
Abstract As a cardinal marker of brain ageing, lifetime brain atrophy obtained from a cross-sectional magnetic resonance image promises to boost statistical powe...
Global incidence of female birdsong is predicted by territoriality and biparental care in songbirds
Genuine quantum scars in many-body spin systems
Abstract Chaos makes isolated systems of many interacting particles quickly thermalize and forget about their past. Here, we show that quantum mechanics hinders chaos in many-body systems: a...
A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses
Determination of trunk neural crest cell fate and susceptibility to splicing perturbation by the DLC1-SF3B1-PHF5A splicing complex
Svalbard winter warming is reaching melting point
Dissipationless transport signature of topological nodal lines
Abstract Topological materials, such as topological insulators or semimetals, usually not only reveal the non-trivial properties of their electronic wavefunction...
Historical changes in overtopping probability of dams in the United States
Late Pliocene growth of the West Antarctic Ice Sheet to near-modern configuration
A self-regulating shuttle for autonomous seek and destroy of microplastics from wastewater
Abstract Microplastics pose a significant environmental challenge, causing harm to organisms through inflammation and oxidative stress. Although traditional adsorbents effectively ca...
Single-atom bridges across biotic-abiotic interfaces facilitate direct electron transfer for solar-to-chemical conversion
ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche
Abstract Acute myeloid leukemia (AML) patients present with CD8 exhaustion signatures, and pharmacologic inhibition of checkpoints can have therapeutic benefit. The alarmin IL-33 and its rec...
Downstream metabolites of (+)-cis-12-oxo-phytodienoic acid function as noncanonical bioactive jasmonates in Arabidopsis thaliana
Ongoing uncoordinated anthropogenic emission abatement promotes atmospheric new particle growth in a Chinese megacity
Abstract Atmospheric new particle growth in diameter is the crucial process determining air quality effects raised by secondary aerosols. However, uncertain mechanisms and long-term trends o...
A human brain network linked to restoration of consciousness after deep brain stimulation
E2F activity determines mitosis versus whole-genome duplication in G2-arrested cells
Structural insights into the roles of PARP4 and NAD+ binding in the human vault cage
A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis
Early intervention with electrical stimulation reduces neural damage after stroke in non-human primates
ATP plays a structural role in Hsp90 function
Abstract Hsp90 is a highly conserved ATP-dependent molecular chaperone that forms a clamp around client proteins. The role of ATP in Hsp90 function is unclear since cell viability requires A...
Microbial consortia for the conversion of biomass into fuels and chemicals
Abstract There is currently significant interest in employing microbial communities for converting lignocellulosic feedstock into chemicals, fuels, and other products of use to humans. Both...