Nature Communications
Articles in this Issue
Scientific literature on carbon dioxide removal revealed as much larger through AI-enhanced systematic mapping
Abstract Carbon dioxide removal plays an important role in any strategy to limit global warming to well below 2 °C. Keeping abreast with the scientific evidence using rigorous evidence synth...
A sodium superionic chloride electrolyte driven by paddle wheel mechanism for solid state batteries
Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin–Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates
Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology
Strategic energy-level modulation in porous heterojunctions: advancing gas sensing through Type-I to Type-II transitions
Light-induced CoOX surface reconstruction in hollow heterostructure for durable photocatalytic seawater splitting
Generating brain-wide connectome using synthetic axonal morphologies
Abstract Recent experimental advancements, including electron microscopy reconstructions, have produced detailed connectivity data for local brain regions. On the other hand, for int...
Scavenger receptor CD163 multimerises to allow uptake of diverse ligands
Abstract CD163 is an archetypal scavenger receptor and mediates detoxification of free haemoglobin. Release of haemoglobin from lysed erythrocytes causes oxidative tissue and organ d...
Deciphering direct transcriptional effects of epigenetic compounds through large-scale new RNA profiling
Abstract Examining direct transcriptional effects of genetic and chemical perturbations is crucial for understanding gene expression mechanisms. Standard RNA-seq experiments often overlook t...
Single-cell expression profiling of bat wing development
Abstract Bats are the only true-flight mammals, with wings formed by elongated digits and wing membranes. Despite the uniqueness, the cellular and molecular aspects of bat wing development r...
Integrin CD103 reveals a distinct developmental pathway of autoreactive thymocytes in TCR transgenic mice
Abstract Clonal deletion through negative selection is critical to eliminate autoreactive T cells in the thymus. Negative selection, however, is imperfect such that some autoreactive thymocy...
Cell-free DNA testing for the detection and prognosis prediction of pancreatic cancer
Raised Leptin and Pappalysin2 cell-free RNAs are the hallmarks of pregnancies complicated by preeclampsia with fetal growth restriction
Abstract Preeclampsia (PE) and fetal growth restriction (FGR) complicate 5-10% of pregnancies and are major causes of maternal and fetal morbidity and mortality. Here we demonstrate that mea...
Anti-sense oligonucleotide probing as a structural platform for studying ribonucleoprotein complex assembly
Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings
No apparent state-dependency of equilibrium climate sensitivity between the Pleistocene glacial and interglacial climate states
A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection
Abstract The universally conserved α-oxoaldehydes glyoxal (GO) and methylglyoxal (MGO) are toxic metabolic byproducts whose accumulation can lead to cell death. In the absence of a known, na...
AcRR1 of Agropyron cristatum boosts wheat yield by regulating grain number per spike and heading date
Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform
Abstract Traditional lectins exhibit broad binding specificity for cell-surface carbohydrates, and generating anti-glycan antibodies is challenging due to low immunogenicity. Neverth...
Comprehensive interaction modeling with machine learning improves prediction of disease risk in the UK Biobank
Signature of magnetoelectric coupling driven finite momentum pairing in 3D ising superconductor
The crystal structure of coronavirus RBD-TMPRSS2 complex provides basis for the discovery of therapeutic antibodies
Diastereoselective synthesis of multi-substituted cyclobutanes via catalyst-controlled regiodivergent hydrophosphination of acyl bicyclobutanes
Engineering oxygen nonbonding states in high entropy hydroxides for scalable water oxidation
Abstract The lattice oxygen oxidation mechanism typically requires the removal of electrons from the metal-oxygen band, which may cause structural instability due to a decrease in the metal-...