Nature Communications
Articles in this Issue
Antigen-specific immunotherapy with a CD4+ T cell neoepitope restrains CD8+ T cell differentiation in murine pancreatic islet grafts
Regulation of physical activity and energy expenditure through Phf6 in the medial preoptic area
Ancient DNA reveals 4000 years of grapevine diversity, viticulture and clonal propagation in France
Nanoscale exchange-bias magnetic tunnel junctions enabled memristive synapse and leaky-integrate-fire neuron for neuromorphic computing
Abstract Neuromorphic computing implemented by spintronic memories offers computational advantages, including in-memory computing capability, high energy efficiency, and near-unlimit...
Tunable and nonlinearity-enhanced dispersive-plus-dissipative coupling in photon-pressure circuits
Abstract Photon-pressure circuits are the circuit implementation of the cavity optomechanical Hamiltonian and discussed for qubit readout, low-frequency quantum...
Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload
Structural transitions in the stepwise assembly of proteasome core particles
Abstract 20S catalytic core particles (CP) of eukaryotic 26S proteasomes are composed of two identical halves comprising 14 distinct subunits. 15S precursor complexes (PC) represent...
Linking photoelectron circular dichroism to the asymmetric total photoemission yield measured in aerosol nanoparticles of tyrosine
Abstract Spectroscopic techniques that are sensitive to molecular chirality are important analytical tools to quantitatively determine enantiomeric excess and purity of chiral molecu...
Bispecific GLP-1/GLP-2 agonism in advanced type 2 diabetes: preclinical characterization and a randomized, double-blind, placebo-controlled phase I trial
Abstract PG-102 is a potency-optimized bispecific Fc fusion protein targeting GLP-1 and GLP-2 receptors. In db/db mouse m...
Limitations of serial cloning in mammals
Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
Abstract The 26S proteasome is the major eukaryotic protease responsible for the degradation of misfolded, damaged, and obsolete regulatory proteins. Commitment to degradation occurs...
Post-pandemic changes in population immunity have reduced the likelihood of emergence of zoonotic coronaviruses
Abstract Infections by endemic viruses, and the vaccines used to control them, often provide cross-protection against related viruses, potentially altering the transmission dynamics...
Unveiling the biodiversity of large DNA viruses in intertidal mudflats via metagenomics
Transient molecular chimerism for exploiting xenogeneic organelles
Abstract The symbiogenetic origin of organelles, such as chloroplasts, is established, and organelle genomes provide evidence of prokaryotic ancestry. Neverthele...
Phage-steering permits antibody-mediated clearance of E. coli K1 from the gut
Post-synthetically modified crown ether-based supramolecular framework for efficient radium sequestration
Frequency-dependent topological polaritons in carbon nanotube array/hBN heterostructures
Abstract Plasmons in carbon nanotubes (CNTs) have attracted significant attention due to their strong spatial confinement and high-quality factors. However, constrained by CNTs’ intr...
Recurring marine phosphorus spikes during major palaeozoic mass extinctions and climate change
Abstract Mass extinctions in the early Palaeozoic have been attributed to global climate change and ocean anoxia with elevated phosphorus (P) proposed as a key driver. However, this...
Copper-hydroxyl interactions drive water-promoted copper surface oxidation and mobility
Crystal symmetry-dependent Orbital Rashba Edelstein effect in epitaxial CuO thin film
Steps to transform African opportunity crops into reality crops
Cardiomyocyte Cyclin-dependent kinase 9 directly binds to and phosphorylates NF-κB p65 subunit to drive cardiac inflammation and remodeling
Emergent discrete space-time crystal of Majorana-like quasiparticles in chiral liquid crystals
Abstract Time crystals spontaneously break the time translation symmetry, as recently has been frequently reported in quantum systems. Here we describe the observation of classical a...
Asymmetric sulfonamide design enabling high-voltage sodium-ion pouch cells in wide temperature
Abstract To advance toward commercial viability, sodium-ion batteries are required to operate under high cut-off voltages and low temperatures. This necessitates...