Nature Communications
Articles in this Issue
Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson’s disease
Abstract Transcranial ultrasound stimulation (TUS) is an emerging method for non-invasive neuromodulation of deep brain structures. However, to date, there is no...
First-line Nivolumab plus FOLFOXIRI/Bevacizumab in advanced RAS/BRAF-mutated colorectal cancer: efficacy, safety and biomarker discovery from the phase II NIVACOR trial
Abstract Immunotherapy achieved remarkable results in patients with deficient mismatch repair (dMMR)/microsatellite instable (MSI) metastatic colorectal carcinoma (mCRC). However, it...
Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hemorrhagic transformation post-tPA thrombolysis
Abstract As an intravenous thrombolytic agent, tissue plasminogen activator (tPA) is limited by hemorrhagic transformation (HT) and a narrow therapeutic time win...
Antimony oxide buffer layer for single- and double-junction perovskite-based solar cells
Abstract Atomic layer-deposited tin oxide serves as an effective buffer layer in perovskite/silicon tandem solar cells due to its efficient charge extraction and...
Zipper-inspired molecular polarity strategy enabling robust adhesive hydroplastics as sustainable plastic substitutes
A dihydrouracil CRBN ligand mitigates IMiD associated safety liabilities in heterobifunctional targeted protein degrader
Contrasting selective signatures of gene expression plasticity in response to antifungal clotrimazole and common environmental stresses in yeast
Rhizobacteria opportunistically boost colonization and impair plant fitness by degrading plant-derived coumarins under iron deficiency
Abstract Plants recruit root-associated bacterial assemblies primarily through the secretion of specialized metabolites, and the resultant rhizospheric microbiot...
Host macrophages/monocytes promote malaria transmission by modulating mosquito microbiota via SR-A-mediated phagocytosis
Anterior and posterior retrosplenial cortex form distinct visuospatial circuits in the mouse
Abstract The retrosplenial cortex (RSC) integrates sensory and mnemonic information to support spatial orientation and navigation, yet how visuospatial processing differs across its...
Active site design enables industrial scale H2O2 electrosynthesis with metal-free catalysts
Atlas of predicted protein complex structures across kingdoms
Editorial Expression of Concern: Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation
Substituent-induced oxidation-reduction molecular organic junction for interfacial hydrogen peroxide photosynthesis
Abstract The distribution of catalytic active sites critically dictates photocatalytic efficiency, but existing catalyst design operate at the same or adjacent s...
Dual-atom Rh-Co catalysts for synergistically boosting nitrile hydrogenation
ENSO phase transition enables prediction of winter North Atlantic Oscillation one year ahead
Abstract The winter North Atlantic Oscillation (NAO) is a dominant mode of climate variability affecting temperature and precipitation across the Northern Hemisphere, yet its predict...
CRISPR tiling deletion screens reveal functional enhancers and allelic compensation effects (ACE) on SIN3A transcription
Abstract Precise transcriptional regulation is critical for cellular function and development, yet the mechanism of this process remains poorly understood for ma...
Ribonuclease 4 Functions in Nociceptor-Mediated Nerve Homeostasis
Abstract The regulation of nociceptor identity and function is essential, as disruptions can significantly influence pain sensation, yet our understanding of the...
Genome-centric metagenomics reveals electroactive syntrophs in a conductive particle-dependent consortium from coastal sediments
Abstract Conductive particles are common in coastal sediments, yet their role in shaping methane-producing communities and pathways remains unclear. We applied g...
All pure multipartite entangled states of qubits can be self-tested
Hh and EGFR-Ras signaling promote distinct steps of tumor progression in the Drosophila follicle epithelium
Abstract Controlled signaling activity is vital for normal tissue homeostasis and oncogenic signaling activation facilitates tumorigenesis. Here, we combine sing...
Acid-tolerant injectable bioadhesive for sutureless repair of large gastric perforation
Abstract Bioadhesives represent promising alternatives to sutures towards gastric perforation management, however, significant challenges persist concerning instant wet adhesion and...