Nature Communications
Articles in this Issue
A lateral hypothalamic region supporting diverse visual processing and modulation of visually-guided behaviour
Abstract Hypothalamic retinal input is traditionally considered distinct from the subcortical pathways supporting vision, specialised to adjust physiology and behaviour alongside var...
Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma
Dynamic dosage changes in X-linked transposable elements during mammalian dosage compensation
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction
Abstract Neural circuits undergo experience-dependent plasticity to form long-lasting memories, but how inhibitory interneurons contribute to this process remains poorly understood....
Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter
Abstract ATP-binding cassette (ABC) transporters use ATP to transport substrates across membranes. In type IV ABC transporters, which include many multidrug resistance (MDR) pumps, c...
Harness of room-temperature polar skyrmion bag in oxide superlattice
Single-cell synaptome mapping of endogenous protein subpopulations in mammalian brain
ELLA: modeling subcellular spatial variation of gene expression within cells in high-resolution spatial transcriptomics
Reply to: Bias-induced electrostatic magnetoresistance in ferromagnet/chiral systems
Hippocampal OLM interneurons regulate CA1 place cell plasticity and remapping
Abstract OLM interneurons selectively target inhibition to the distal dendrites of CA1 pyramidal cells in the hippocampus but the role of this unique morphology...
Extended fear learning enhances excitatory and inhibitory synaptic transmission onto amygdala engram cells
Measurement of correlated charge noise in superconducting qubits at an underground facility
Abstract The charge environment of superconducting qubits may be studied through the introduction of controlled, quantified amounts of ionizing radiation. We mea...
5-Formylcytosine is not a prevalent RNA modification in mammalian cells
A node-localized efflux transporter for loading iron to developing tissues in rice
Importance of ocean dynamics in the onset and persistence of the 2013-15 and 2019-20 northeast Pacific marine heatwaves
Abstract Large-scale marine heatwaves in the mid-latitude northeast Pacific have garnered significant attention due to their vast spatial extent, intensity, prolonged duration, and d...
Graph-based pangenomes and pan-phenome provide a cornerstone for eggplant biology and breeding
A monoclonal antibody that inhibits the shedding of CD16a and CD16b and promotes antibody-dependent cellular cytotoxicity against tumors
Abstract CD16a triggers antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis by natural killer (NK) cells and macrophages in anti-tumor immunity. However, CD16a undergoes...
Targeting polyamine metabolism and ferroptosis enhances the efficacy of KRAS-targeted therapy depending on KEAP1 status
A software platform for real-time and adaptive neuroscience experiments
Abstract Current neuroscience research is often limited to testing predetermined hypotheses and post hoc analysis of already collected data. Adaptive experimenta...
CryoEM and computational modeling structural insights into the pH regulator NBCn1
Abstract Breast cancer cells survive despite being exposed to a toxic acidic extracellular environment, by utilizing the NBCn1 transporter. The molecular basis f...
Exploiting neuro-inspired dynamic sparsity for energy-efficient intelligent perception
Abstract Artificial intelligence (AI) has made significant strides towards efficient online processing of sensory signals at the edge through the use of deep neural networks with eve...
The economic, agricultural, and food security repercussions of a wild pollinator collapse in Europe
Abstract Biodiversity conservation policies often face resistance, yet the global agri-food system’s vulnerability to ecosystem service declines, such as wild pollinator losses, rema...
Continuous exchange of an inner-membrane ring component is required for assembly and function of the type III secretion system
Abstract Major bacterial pathogens manipulate eukaryotic target cells by injecting effector proteins through type III secretion systems (T3SS). Recent in situ ob...
Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis
Abstract Our understanding of the immune response in tuberculosis (TB) remains incomplete. This applies in particular to extrapulmonary TB (EPTB), a highly heterogeneous disease affe...
Atomic-scale insights into surface reconstruction and transformation in Co-Cr spinel oxides during the oxygen evolution reaction
Abstract Optimizing the activity and longevity of oxygen evolution reaction (OER) electrocatalysts requires an atomic-scale understanding of multiple reconstruct...