Nature Communications
Articles in this Issue
Structural Insights into De Novo Promoter Escape by Mycobacterium tuberculosis RNA Polymerase
Abstract Transcription in bacteria is a multi-step process. In the first step, contacts between RNA polymerase and the promoter DNA must be established for trans...
Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling
Abstract Understanding kinase action requires precise quantitative measurements of their activity in vivo. In addition, the ability to capture spatial information of kinase activity...
Mutual inhibition between EPFL2 and auxin extends the intervals of periodic leaf morphogenesis
Edge-condensation to access a crystalline planar icosagen cation with σ-aromaticity
All-plasmonic sub-terahertz wireless communication link
Abstract A promising approach to increase wireless capacity is the transition to sub-Terahertz carrier frequencies (0.1–0.3 THz). While traditional high-frequency approaches employ I...
Self-assembled polymeric nanosheet-anchored nanofiber membrane for emulsion separation
Pressure anisotropy-driven instabilities regulate the jovian magnetodisk
Film surface assemblies from chemically distinct block copolymer micelles
Boosting the brightness of aggregation-caused quenching chromophore-based covalent organic frameworks via energy level matching strategy
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome
Abstract The bacterial chaperonin GroEL/ES promotes protein folding post-translation by transiently encapsulating client proteins within a central chamber. GroEL also binds translati...
Decoupling structural molecular dynamics from excited state lifetimes using few-femtosecond ultraviolet resonant dispersive waves
Abstract Optical sources exploiting resonant dispersive wave (RDW) emission are set to revolutionize ultrafast science. We demonstrate this approach by investigating excited state dy...
Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis
Abstract Dysregulation of heat shock protein DNAJA2 induces genomic instability and was consequently hypothesized to promote tumorigenesis. However,...
A century of change in the California Current: upwelling system amplifies acidification
Abstract Predicting the pace of acidification in the California Current System (CCS), a productive upwelling system that borders the west coast of North America,...
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
Abstract Inflammation and excess cytokine release are hallmarks of severe COVID-19. While programmed cell death is known to drive inflammation, its role in SARS-CoV-2 pathogenesis re...
qMaLioffG: a genetically encoded green fluorescence lifetime-based indicator enabling quantitative imaging of intracellular ATP
Observation of momentum-band topology in PT-symmetric Floquet lattices
Abstract Momentum-band topology is a groundbreaking concept in multidisciplinary physics. Unlike the conventional energy-band topology, it defines a distinctive band topology within...
Developmentally regulated genes drive phylogenomic splits in ovule evolution
Ultra-mild bisulfite outperforms existing methods for 5-methylcytosine detection with low input DNA
Abstract We present Ultra-Mild Bisulfite Sequencing (UMBS-seq), a method for 5-methylcytosine (5mC) detection that minimizes DNA degradation and background noise. UMBS-seq outperform...
Human intestinal fungus Clavispora lusitaniae attenuates colitis through Pyruvate decarboxylase-derived Indole-3-ethanol
Cascaded nonlinear down-conversion in poling-free lithium niobate nanophotonic waveguides
DNA viral community enhances microbial carbon fixation capacity via auxiliary metabolic genes in contaminated soils
Abstract Soil is the largest organic matter repository on land and the virosphere is an essential component of soil carbon cycling. While a few carbon-related au...
Iron absorption and loss, and efficacy of iron supplementation with and without prebiotics in children with virally suppressed HIV: three prospective studies in South Africa
Abstract Children living with HIV are at risk for iron deficiency, yet optimal strategies for prevention and treatment remain unclear. Here, we investigate iron...