Nature Communications
Articles in this Issue
Polyethylene hydrogenolysis to liquid products over bimetallic catalysts with favorable environmental footprint and economics
Greater benefits of immediate nirmatrelvir-ritonavir initiation for post-COVID outcomes: a population-based retrospective cohort study
LUBAC modulates CBM complex functions downstream of TRAF6 in T cells
Abstract The CARD11-BCL10-MALT1 (CBM) complex drives NF-κB signaling and MALT1 protease activation after T cell receptor (TCR) stimulation, forming a central sig...
Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma
Abstract Human isotopic tracer studies are key for in vivo studies of cancer metabolism. Yet, the effects of sampling conditions on the tissue metabolome remain...
Development of a targeted BioPROTAC degrader selective for misfolded SOD1
Abstract The accumulation of misfolded proteins underlies a broad range of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Due to thei...
131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma
Abstract The coexistence of asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) is associated with allergic phenotypes, disease severity and failure...
Probabilistic classification of late treatment failure in uncomplicated falciparum malaria
Abstract Distinguishing treatment failure (recrudescence) from reinfection in uncomplicated falciparum malaria is essential for characterising antimalarial treat...
Breaking barriers in crosslinking mass spectrometry with enhanced throughput and sensitivity using Orbitrap Astral
Abstract Crosslinking mass spectrometry is an essential tool for probing protein-protein interactions and structural organization. We here compare Orbitrap Astral and Orbitrap Eclips...
Overcoming size limits with dynamic templates enabling large area single crystal nanowire arrays for photodetectors
Abstract Ordered one dimensional perovskite single-crystal nanowire arrays, which combine high surface-to-volume ratios, directional charge transport, and mechan...
Prognostic value of an abnormal chest X-ray result in predicting the development of tuberculosis
Turbulent isopycnal mixing dominates thermohaline transformations of intermediate ocean waters
Lysosomal and mTORC1 signaling dysregulation underpin the pathology of spastic paraplegia type 80
A mitochondria-targeted fluoropolymer nanoparticle with inherent mitophagy-inducing and red fluorescence properties for treatment of atherosclerosis
Microglia alter sex-specific cerebellar myelination following placental hormone loss
The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling
Abstract The detection of cytosolic dsDNA by the cyclic GMP-AMP synthase (cGAS) is tightly regulated to avoid pathological inflammatory responses. Here, we show that the methyl-CpG-b...
Two-step grain boundary diffusion mechanism of a dopant accompanied by structural transformation
TUSC3 regulates ERMA-mediated Mg2+ uptake for synaptic function and neurodevelopment
Electrochemical deutero-(di)carboxylations for the preparation of deuterium-labeled medicinal building blocks
Reference genome and population genomic analyses reveal insight into herbicide tolerance in Avena fatua L.
Multifunctionally diverse alkaline phosphatases of Alteromonas drive the phosphorus cycle in the ocean
Development of the preterm infant gut and gastric residuals microbiome
GABA-independent activation of GABAB receptor by mechanical forces
High-speed antiferromagnetic domain walls driven by coherent spin waves
Poly(imidazolium ester) antibiotic forms intracellular polymer-nucleic acid biomolecular condensates and fight drug-resistant bacteria
Critical length screening enables 19% efficiency in thick-film organic solar cells
Abstract The commercialization of organic solar cells (OSCs) requires thick-film active layers, yet current thick-film-compatible acceptor selection based on zero-field mobility is u...