Nature Communications
Articles in this Issue
Visual awareness sharpens and accelerates attentional sampling through enhancing inhibitory neural modulation in the attention network
Quantum teleportation with dissimilar quantum dots over a hybrid quantum network
RAF inhibitors activate the integrated stress response by direct activation of GCN2
Abstract Paradoxical activation of wild type RAF by chemical RAF inhibitors (RAFi) is a well-understood ‘on-target’ biological and clinical response. In this study, we show that a ra...
β-adrenergic signaling blockade attenuates metastasis through activation of cytotoxic CD4 T cells
Targeting tumor-intrinsic BCL9 reverses immunotherapy resistance by eliciting macrophage-mediated phagocytosis and antigen presentation
Multivariate genome-wide analyses of insulin resistance unravel novel loci and therapeutic targets for cardiometabolic health
Mechanical and structural analysis of graphene-PMMA laminate
Impact of a transient neonatal visual deprivation on the development of the ventral occipito-temporal cortex in humans
MicroRNA-mediated metabolic disruption as an emerging driver of alcohol use disorder
KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
Abstract Lineage plasticity is a hallmark of pancreatic ductal adenocarcinoma (PDAC) and contributes to tumor heterogeneity and therapeutic resistance. Here, we identify KLF5 as a dy...
Balancing mechanical-thermal-electrical properties in cellulose ionogels via crystallization-induced molecular assembly
Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis
Vaginal microbiome and sexually-transmitted pathogens in Chinese reproductive-age women: a multicentre cross-sectional and longitudinal cohort study
A base-stabilized germavinylidene
Bidirectional quantitative scattering microscopy
Abstract Quantitative phase microscopy (QPM) and interferometric scattering (iSCAT) microscopy are powerful label-free imaging techniques that are widely used in biomedical applicati...
Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding
scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples
Abstract Formalin-fixed paraffin-embedded (FFPE) samples are the gold standard for tissue preservation in clinical and research settings. Current single-cell chromatin accessibility...
GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology
Abstract GWAS of primary angle-closure glaucoma have identified eight loci conferring risk in Asian populations. However, it remains unclear whether the genetic risk factors for the...
A preserved TGFβ cytostatic response through DLD-mediated metabolic modulation undermines anti-TGFβ therapy in gastric cancer
A functionally complete logic gate in a soft photoresponsive hydrogel
Unlocking ultrafast hot hole transport in transition metal oxides governed by the nature of optical transitions
Abstract The intrinsically low carrier mobility of transition metal oxides within the polaron transport framework fundamentally limits their optoelectronic perfo...
Fibroblast growth factor signaling induces a chondrocyte-like state of peripheral nerve fibroblast during aging
Abstract During aging, peripheral nerves undergo structural and cellular changes that trigger loss of function, impair quality of life, and increase disease risk. During peripheral n...
Cortical hierarchy underlying homeostatic sleep pressure alleviation
Doppler effect tailoring: extra-red shift of structured light
Top-down perceptual inference shaping the activity of early visual cortex
Abstract Deep discriminative models provide remarkable insights into hierarchical processing in the brain by predicting neural activity along the visual pathway. However, these model...