Nature Communications
Articles in this Issue
Polaritonic Fourier crystal
USP7 V517F mutation as a mechanism of inhibitor resistance
FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice
Abstract Early life stress (ELS) can increase vulnerability to psychiatric disorders, but also trigger resilience. FKBP51 has been associated with an increased risk for developing psychiatri...
ER O-glycosylation in synovial fibroblasts drives cartilage degradation
Abstract How arthritic synovial fibroblasts (SFs) activate cartilage ECM degradation remains unclear. GALNT enzymes initiate O-glycosylation in the Golgi; when relocated to the ER, t...
Deep representation learning for clustering longitudinal survival data from electronic health records
Abstract Precision medicine requires accurate identification of clinically relevant patient subgroups. Electronic health records provide major opportunities for leveraging machine le...
Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization
Abstract The initial setting of telomere length during early life in each individual has a major influence on lifetime risk of aging-associated diseases; however there is limited knowledge o...
High-fidelity remote entanglement of trapped atoms mediated by time-bin photons
Abstract Photonic interconnects between quantum processing nodes are likely the only way to achieve large-scale quantum computers and networks. The bottleneck in such an architecture is the...
Deep learning prioritizes cancer mutations that alter protein nucleocytoplasmic shuttling to drive tumorigenesis
Chiral europium halides with high-performance magnetic field tunable red circularly polarized luminescence at room temperature
Solar-powered light-modulated microwave programmable metasurface for sustainable wireless communications
Groundwater quality evolution across China
Amplified multipartite entanglement witnessed in a quantum critical metal
Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
Pervasive impact modification of pristine lunar clasts
Copper-catalysed dynamic kinetic asymmetric C−O cross-coupling to access chiral aryl oxime ethers and diaryl ethers
In-depth plasma N-glycoproteome profiling using narrow-window data-independent acquisition on the Orbitrap Astral mass spectrometer
Abstract Recently, a conceptually new mass analyzer was introduced by pairing a quadrupole Orbitrap mass spectrometer with an asymmetric track lossless (Astral™) analyzer. This system provid...
Author Correction: Unveiling mechanisms and onset threshold of humping in high-speed laser welding
Transient non-soluble noble metal transport in hydrothermal ore systems
Abstract The transport of noble metals (Au, Ag) by metal-rich melts in hydrothermal ore systems is now acknowledged as a complementary mechanism to complexing ligands in solution. However, i...
Observing time-dependent energy level renormalisation in an ultrastrongly coupled open system
Abstract Understanding how strong coupling and memory effects influence energy levels in open quantum systems is a fundamental challenge. Here, we experimentally probe these effects in a two...
Wafer-scale platform for on-chip 3D radio frequency lumped passive components using metal self-rolled-up membrane technique
HC-Pro inhibits HEN1 methyltransferase activity, leading to autophagic degradation of AGO1
Self-assembly, interlocking, interconversion and anion-binding catalysis in phenoxazine-based Pd2L4 and Pd4L8 coordination cages
Functionally constrained human proteins are less prone to mutational instability from single amino acid substitutions
Abstract Missense mutations that disrupt protein structural stability are a common pathogenic mechanism in human genetic disease. Here, we quantify potential disruption of protein stability...
Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases
Plasma exchange and radiation resensitize immunotherapy-refractory melanoma: a phase I trial
Abstract Immune checkpoint inhibitors (ICI) are effective for advanced melanoma. However, most develop ICI resistance. Tumor-derived soluble PD-L1 (sPD-L1) and o...