Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases

Charles W. O’Donnell; Jeremiah D. Farelli; Houda Belaghzal; Justin Chen; Lauren Beech; James Sullivan; Chevaun Morrison-Smith; Stephen Siecinski; Adam Katz; Samuel Mildrum; Mayur Gurnani; Prachi Dhanania; Caitlyn R. Webb; Giuliana Castello Coatti; Pranjali Rumale; Daniel F. G. Costa; Marcus I. Gibson; Yaoyu E. Wang; Joseph V. Newman; Thomas G. McCauley

doi:10.1038/s41467-025-57920-5

Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases

C Charles W. O’Donnell J Jeremiah D. Farelli H Houda Belaghzal J Justin Chen L Lauren Beech J James Sullivan C Chevaun Morrison-Smith S Stephen Siecinski A Adam Katz S Samuel Mildrum M Mayur Gurnani P Prachi Dhanania C Caitlyn R. Webb G Giuliana Castello Coatti P Pranjali Rumale D Daniel F. G. Costa M Marcus I. Gibson Y Yaoyu E. Wang J Joseph V. Newman T Thomas G. McCauley

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published March 13, 2025

DOI 10.1038/s41467-025-57920-5

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

C

Charles W. O’Donnell

J

Jeremiah D. Farelli

H

Houda Belaghzal

J

Justin Chen

L

Lauren Beech

J

James Sullivan

C

Chevaun Morrison-Smith

S

Stephen Siecinski

A

Adam Katz

S

Samuel Mildrum

M

Mayur Gurnani

P

Prachi Dhanania

C

Caitlyn R. Webb

G

Giuliana Castello Coatti

P

Pranjali Rumale

D

Daniel F. G. Costa

M

Marcus I. Gibson

Y

Yaoyu E. Wang

J

Joseph V. Newman

T

Thomas G. McCauley

Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases

Article Details

Journal Info

Authors (20)

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