Nature Communications
Articles in this Issue
snCED-seq: high-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues
Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men
Abstract Given the various roles of testosterone in men’s health, we conducted a multi-ancestral genetic analysis of total testosterone, free testosterone, SHBG, and hypogonadism in men with...
Feedback-responsive cell factories for dynamic modulation of the unfolded protein response
LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers
Abstract The efficacy of molecularly targeted therapies may be limited by co-occurring mutations within a tumor. Conversely, these alterations may confer collate...
Trait coordination and trade-offs constrain the diversity of water use strategies in Mediterranean woody plants
Precise control of tibial nerve stimulation for bladder regulation via evoked compound action potential feedback mechanisms
Snord67 promotes breast cancer metastasis by guiding U6 modification and modulating the splicing landscape
Abstract Previously considered “housekeeping” genes, small nucleolar RNAs (snoRNAs) are increasingly understood to have wide-ranging functions in cancer, yet their role in metastasis has bee...
Moiré collective vibrations in atomically thin van der Waals superlattices
T cell toxicity induced by tigecycline binding to the mitochondrial ribosome
Abstract Tetracyclines are essential bacterial protein synthesis inhibitors under continual development to combat antibiotic resistance yet suffer from unwanted side effects. Mitorib...
An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models
Abstract Although vaccines are usually given intramuscularly, the intranasal delivery route may lead to better mucosal protection and limit the spread of respiratory virus while easing admin...
PWWP3A disrupts the assembly of VISA/MAVS signalosome to inhibit innate immune response against RNA viruses
Self-organized spatiotemporal quasi-phase-matching in microresonators
Abstract Quasi-phase-matching (QPM) is a widely adopted technique for mitigating stringent momentum conservation in nonlinear optical processes such as second-harmonic generation (SHG). It e...
Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease
Abstract The viscoelastic properties of tissues influence their morphology and cellular behavior, yet little is known about changes in these properties during brain malformations. Lissenceph...
Author Correction: Highly oxidized products from the atmospheric reaction of hydroxyl radicals with isoprene
Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy
Artificial intelligence driven 3D reconstruction for enhanced lung surgery planning
Filamin C dimerisation is regulated by HSPB7
Abstract The biomechanical properties and responses of tissues underpin a variety important of physiological functions and pathologies. In striated muscle, the actin-binding protein filamin...
Engineering transverse cell deformation of bamboo by controlling localized moisture content
Unveiling a large fraction of hidden organosulfates in ambient organic aerosol
Abstract Organosulfates are key compounds driving the anthropogenic enhancement of ambient organic aerosol, however, total organosulfate quantification remains elusive due to their molecular...
Sex-differentiated placental methylation and gene expression regulation has implications for neonatal traits and adult diseases
Abstract Sex differences in physiological and disease traits are pervasive and begin during early development, but the genetic architecture of these differences is largely unknown. Here, we...
Frustrated charge density wave and quasi-long-range bond-orientational order in the magnetic kagome FeGe
Abstract The intrinsic frustrated nature of a kagome lattice is amenable to the realization of exotic phases of matter, such as quantum spin liquids or spin ices...