Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy

Z Zhixiang Chen (Future Technology School, Shenzhen Technology University) H Harshil Dhruv X Xuqing Zhang R Rohan Kalyan Rej L Longchuan Bai D Donna McEachern P Paul Kirchhoff R Rakesh Nagilla L Larry J. Jolivette C Cory T. Rice P Peter Orth C Corey O. Strickland E E. Scott Priestley H Helai P. Mohammad M Meilin Wang B Bo Wen (School of Physics and Electronics) D Duxin Sun Z Zhihua Sui S Shaomeng Wang

Article Details

Volume / Issue Vol. 16, Issue 1
Published May 01, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

Z

Zhixiang Chen

Future Technology School, Shenzhen Technology University

H

Harshil Dhruv

X

Xuqing Zhang

R

Rohan Kalyan Rej

L

Longchuan Bai

D

Donna McEachern

P

Paul Kirchhoff

R

Rakesh Nagilla

L

Larry J. Jolivette

C

Cory T. Rice

P

Peter Orth

C

Corey O. Strickland

E

E. Scott Priestley

H

Helai P. Mohammad

M

Meilin Wang

B

Bo Wen

School of Physics and Electronics

D

Duxin Sun

Z

Zhihua Sui

S

Shaomeng Wang