Nature Communications
Articles in this Issue
METTL14 regulates chondrogenesis through the GDF5–RUNX–extracellular matrix gene axis during limb development
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the U.S. Both rare and common germline variants contribute to PDAC risk. Here, we fine...
Characteristics of leaf nutrient resorption efficiency in Tibetan alpine permafrost ecosystems
Abstract Nutrient resorption is an important strategy for nutrient conservation, especially in permafrost ecosystems where plant growth is limited by nutrients. Based on the measurements mai...
Self-supervised learning for label-free segmentation in cardiac ultrasound
Abstract Segmentation and measurement of cardiac chambers from ultrasound is critical, but laborious and poorly reproducible. Neural networks can assist, but supervised approaches require th...
Epitope-optimized vaccine elicits enduring immunity against swine influenza A virus
Rhizosphere-triggered viral lysogeny mediates microbial metabolic reprogramming to enhance arsenic oxidation
O-GlcNAcylation reduces proteome solubility and regulates the formation of biomolecular condensates in human cells
The motor neuron m6A repertoire governs neuronal homeostasis and FTO inhibition mitigates ALS symptom manifestation
Abstract Amyotrophic lateral sclerosis (ALS) is a swiftly progressive and fatal neurodegenerative ailment marked by the degenerative motor neurons (MNs). Why MNs are specifically susceptible...
Concurrently enhanced piezoelectric performance and curie temperature in stressed lead-free Ba0.85Ca0.15Ti0.9Zr0.1O3 ceramics
Gibberellin signaling regulates pectin biosynthesis in Arabidopsis
Learning tissue representation by identification of persistent local patterns in spatial omics data
Abstract Spatial omics data provide rich molecular and structural information on tissues. Their analysis provides insights into local heterogeneity of tissues and holds promise to im...
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures
Abstract In Alzheimer’s disease, amyloid beta (Aβ) and tau pathology are thought to drive synapse loss. However, there is limited information on how endogenous l...
A cytosolic glyoxylate shunt complements the canonical photorespiratory pathway in Arabidopsis
Near-ultrastrong nonlinear light-matter coupling in superconducting circuits
Reinforcement learning increasingly relates to memory specificity from childhood to adulthood
Viscoelastic extracellular matrix enhances epigenetic remodeling and cellular plasticity
Abstract Extracellular matrices of living tissues exhibit viscoelastic properties, yet how these properties regulate chromatin and the epigenome remains unclear....
Advances in the social construction of energy management and energy efficiency in industry
GōMartini 3: From large conformational changes in proteins to environmental bias corrections
Nickel Ion Induced Multistage Assembly of Th13 Cluster
Heat and hospitalization risks among people with disabilities in South Korea
Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems
Glycosylation of serine/threonine-rich intrinsically disordered regions of membrane-associated proteins in streptococci
2D Cd metal contacts via low-temperature van der Waals epitaxy towards high-performance 2D transistors
AI-driven discovery of synergistic drug combinations against pancreatic cancer
Abstract Pancreatic cancer treatment often relies on multi-drug regimens, but optimal combinations remain elusive. This study evaluates predictive approaches to identify synergistic...
Daily rainfall variability controls humid heatwaves in the global tropics and subtropics
Abstract Humid heatwaves are a growing risk to human and animal health, especially in tropical regions. While there is established research on dry-bulb temperature heatwaves, greater...