Nature Communications
Articles in this Issue
Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study
Abstract CD200R is a checkpoint inhibitory receptor central to the pathogenesis of inflammatory skin disease. Here we describe the development and phase 1 clinical study (NCT03750643) of uce...
Pinpointing the thermal history of lunar basaltic meteorites in a nutshell
N 6-methyladenosine modifications stabilize phosphate starvation response–related mRNAs in plant adaptation to nutrient-deficient stress
Endemism shapes viral ecology and evolution in globally distributed hydrothermal vent ecosystems
Abstract Viruses are ubiquitous in deep-sea hydrothermal vents, where they influence microbial communities and biogeochemistry. Yet, viral ecology and evolution remain understudied i...
Structure and transport mechanism of human riboflavin transporters
Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex
Abstract Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity c...
Structure Sensitivity and Catalyst Restructuring for CO2 Electro-reduction on Copper
Abstract Cu is the most promising metal catalyst for CO 2 electroreduction (CO 2...
Quantum simulation of spin-boson models with structured bath
Independent domestication and cultivation histories of two West African indigenous fonio millet crops
Abstract Crop evolutionary history and domestication processes are key issues for better conservation and effective use of crop genetic diversity. Black and white fonio (Digitaria iburua and...
Natural genetic variation quantitatively regulates heart rate and dimension
Abstract The polygenic contribution to heart development and function along the health-disease continuum remains unresolved. To gain insight into the genetic bas...
High-entropy sulfoselenide as negative electrodes with fast kinetics and high stability for sodium-ion batteries
Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy
CAR macrophages with built-In CD47 blocker combat tumor antigen heterogeneity and activate T cells via cross-presentation
Energy requirements for securing wellbeing in Switzerland and the space for affluence and inequality
Abstract The idea that human needs should be secured for all people is largely uncontroversial, and recent research demonstrates that decent living standards could be secured for all, global...
Internal hydrogen-bond enhanced two-electron oxygen reduction reaction for π-d conjugated metal-organic framework to H2O2 synthesis
Cathodic oxygen reduction-enabled rhodium-catalyzed (5 + 1) C–H/O–H annulation inspired by fuel cells
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression
Quantum melting of generalized electron crystal in twisted bilayer MoSe2
Efficient spin accumulation carried by slow relaxons in chiral tellurium
Abstract Efficient conversion between charge currents and spin signals is crucial for realizing magnet-free spintronic devices. However, the strong spin-orbit coupling that enhances this con...
Closed-loop control of theta oscillations enhances human hippocampal network connectivity
Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignancies
Abstract Myeloid malignancies exhibit considerable heterogeneity with overlapping clinical and genetic features among subtypes. We present a data-driven approach that integrates muta...
Modelling the species-area relationship using extreme value theory
Abstract The nested species-area relationship, obtained by counting species in increasingly larger areas in a nested fashion, exhibits robust and recurring qualitative and quantitative patte...
Loss of sea ice alters light spectra for aquatic photosynthesis
Abstract The dramatic loss of sea ice due to global warming is changing light conditions for marine primary production, but exactly how is not well understood. Previous studies revealed that...