Nature Communications
Articles in this Issue
Clinically-applicable prediction of hospital stay and patient similarity retrieval in paediatric cardiology using machine learning
Abstract Paediatric cardiology presents challenges due to the rarity and complexity of conditions like congenital heart disease. Using retrospective electronic healthcare records fro...
Non-Arrhenius threshold switching by field-driven dipolar ordering
Abstract The long-standing challenge in resolving the atomic-scale threshold switching mechanism in amorphous chalcogenides, fundamental constraint on further development of promisin...
Assessing corporate transition plans using a production asset-based planning approach
Engineering B cells to express fully customizable antibodies with enhanced Fc functions
Wnt signaling regulates passive cell competition in the retina by inducing differential cell adhesion
Network topology of the gut microbiome associates with metabolic health in obesity
Abstract Obesity is a heterogeneous condition comprising a continuum of phenotypes with various metabolic and inflammatory profiles. Metabolically healthy obesity (MHO) identifies in...
A characteristic length linking oxygen transport and product selectivity in chemical looping methane anaerobic oxidation
Multiscale machine learning molecular mechanics for mechanism and stereoselectivity of Diels-Alderase catalysis
Abstract Enzymes catalyze complex chemical transformations with remarkable efficiency and selectivity, yet their atomistic mechanisms remain challenging to captu...
Organocatalytic atom transfer radical polymerization with light and pH dual-gated regulation
Nanobody-mediated control of long RSH Rel and RelA catalysis by restriction of their conformational landscape
Abstract Long RSH enzymes, Rel and RelA, are master regulators of bacterial (p)ppGpp alarmones levels. Bifunctional Rel transitions between a compact hydrolysis-...
TBK1 restricts IRGQ-mediated autophagy
Abstract The autophagy-lysosome system directs the degradation of a wide variety of cytoplasmic cargo such as damaged organelles, protein aggregates, and invading pathogens. The auto...
Discovery and synthesis of flueggeacosines D–F and securingine J
BromoCatch: a self-labelling tag platform for protein modification and live cell imaging
Abstract Visualizing and manipulating proteins in live cells is crucial for studying complex biological processes. Self-labelling protein (SLP) tags such as HaloTag and SNAP-tag are...
Double-stranded RNA and ROS scavenging nanoplatform for modulating skin inflammation
Aerogel-involved triple-state viscoelastic fluidic materials enable high-efficiency dual-purpose energy management
Site-specific glycosylation of Sec24D and myoferlin recruit ERGIC to ER exit sites for collagen trafficking
Terahertz generation and detection through gain-enhanced interband photomixing in quantum well structures
Abstract Terahertz waves hold immense potential across diverse fields, including healthcare monitoring, biomedical imaging, precision navigation, high-speed communication, security s...
A tunable CTD grammar governs the spatial programming of the transcription cycle
Extensive cryptic circulation sustains mpox among men who have sex with men
Abstract Sporadic cases of clade IIb mpox continue to be notified among men who have sex with men, with most lacking identifiable transmission links. To resolve underlying dynamics,...
CLUES A Comprehensive Workflow for Integrating Geospatial Data in Biomedical Research
Abstract Environmental exposures play a critical role in shaping physical and mental health, yet integrating such data into biomedical research remains technically complex and fragme...
Regionally divergent drivers behind transgressions of the freshwater change planetary boundary
Abstract Human-driven freshwater change relates to elevated Earth system risks, which motivates analysis to better understand its global characteristics. Here, we analyse global and...
Multipolar electric and magnetic contributions to sum-frequency generation spectra reveal biaxial interfacial water structure
Abstract Liquid interfaces play central roles in biological and physicochemical processes. Sum-frequency-generation (SFG) spectroscopy is intrinsically interface-specific, but the in...
Sub-picosecond extraction of hot carriers in black phosphorus
Abstract Harvesting hot carriers before they lose energy to the lattice is a critical route toward surpassing the conventional thermodynamic limit in optical-to-electrical (O-E) conv...