Nature Communications
Articles in this Issue
Shared cloud interactions unveil a candidate binary-system supernova pair with no known analogue
Abstract IC 443 is one of the most extensively studied supernova remnants in the Galaxy, yet the surrounding region remains shrouded in mystery. Here we show tha...
Host-directed treatments for tuberculous meningitis utilizing a multi-platform approach across mouse and human models
Quantifying UK coastal flood exposure under future sea-level rise to 2300
Abstract The latest Intergovernmental Panel on Climate Change assessment report highlighted the potential for more than 15 m of global sea-level rise by 2300. In this study, we explo...
Thymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy
Abstract Chronic inflammation increases with age and contributes to cancer progression and therapeutic resistance, yet the mechanisms underlying this process remain incompletely unde...
Symmetry-driven gating of TRPM8 by PIP2 and menthol
Mitochondrial translation termination, recycling, reinitiation, and rescue for in-frame and out-of-frame contexts
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease
Trans-scale spin Seebeck effect in nanostructured bulk composites based on magnetic insulator
Abstract The spin Seebeck effect enables thermoelectric conversion through thermally generated spin currents in magnetic materials, offering a promising transverse geometry for scala...
Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission
Abstract Active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) requires intensive immunosuppressive therapy, but continued treatment beyond remission ris...
Analysis of 14q12 microdeletions reveals novel regulatory loci for the neurodevelopmental disorder-related gene FOXG1
Spatial multi-omics identifies early synaptic pruning and context-specific dopaminergic vulnerability in synucleinopathies
Abstract Parkinson’s disease (PD) is characterized by degeneration of dopaminergic neurons in the substantia nigra pars compacta, but the molecular events preceding neuronal loss rem...
Quantum adiabatic transport in a quantum anomalous Hall insulator
Abstract An exceptional trait of the quantum Hall effect is quantum adiabatic transport, dissipationless quantized edge transport that is robust to bias voltages multiple orders of m...
Leiomodin 2 is a processive pointed-end elongator of actin filaments
Statin-induced lipid carrier stress reveals a conserved vulnerability in β-lactam-resistant Gram-positive bacteria
Abstract Methicillin-resistant Staphylococcus aureus resists β-lactam antibiotics through the allosteric transpeptidase p...
Mechanism of actin thin filament pointed-end elongation by leiomodin
Hippocampal ripples initiate cortical dimensionality expansion for memory retrieval
Abstract How are past experiences reconstructed from memory? Learning is thought to compress external inputs into low-dimensional hippocampal representations, later expanded into hig...
Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions
Abstract The cohesin complex structures the interphase genome of human cells by extruding loops and organizing topologically associating domains (TADs), yet how chromatin state regul...
An integrated multi-THz tunable linear isolator based on electro-optic non-reciprocal strong coupling
Resolving Abrikosov vortex entry in superconducting nanostring resonators via displacement-noise spectroscopy in cavity optomechanics
The Japanese Palaeolithic deserves more attention in Western narratives about human expansion across Asia
Unraveling daily dynamics of supraglacial lakes in response to hydrological pulses and anomalous climate signals
Abstract Mass loss from debris-covered glaciers in High Mountain Asia drives the expansion of small supraglacial lakes (SGLs) and changes the occurrence patterns...
Enhancing sit-to-stand transitions and walking efficiency in older adults with a soft robotic suit
Abstract Age-related declines in muscle strength and neuromuscular control make sit-to-stand transitions and walking progressively more difficult, compromising mobility and independe...
Understanding the European energy crisis through structural causal models
Abstract Natural gas supplies in Europe were disrupted and energy prices soared in the context of Russia’s invasion of Ukraine. Electricity prices in France experienced the largest r...
Meta-analytic evidence for distinct neural correlates of conditioned versus verbally induced placebo analgesia
Abstract Placebo analgesia demonstrates that belief and expectation can significantly alter pain, even without active treatment. Placebo analgesia can be induced...