Nature Communications
Articles in this Issue
Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial
Microbial engraftment and immune regulation during fecal microbiota transplantation and immune checkpoint inhibitor therapy
Author Correction: Integrative omics of the genetic basis for wheat WUE and drought resilience reveal the function of TaMYB7-A1
Miniature Dungey-like cycle at Mars
Abstract With its non-uniform distribution of crustal magnetic fields, Mars exhibits complex and highly variable auroral patterns related to both planetary rotation and solar wind co...
Nanofiber-like polar configurations enable ultrahigh energy storage in relaxor ferroelectrics via high-entropy design
Activity-dependent ribosome profiling reveals the landscape of canonical and non-canonical translation in brain tissue
Abstract Neural activity-dependent translation is essential for synaptic plasticity and diverse brain functions. Translation involves not only canonical main ope...
Finite-temperature criticality through quantum annealing
Abstract Critical phenomena at finite temperature underpin a broad range of physical systems, yet their study remains challenging due to computational bottlenecks near phase transiti...
Author Correction: Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma
SYCP2 recruits HORMAD2 to chromosome axes for unsynapsed chromatin silencing and synapsis surveillance in meiosis
Abstract Faithful chromosome segregation during meiosis requires accurate recombination and synapsis of homologous chromosomes. These processes are monitored in mammals by checkpoint...
HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous recombination repair
Abstract R loop homeostasis is critical for DNA double-strand break (DSB) repair; however, how R loops are resolved in this context is poorly understood. Here, we define HELZ as a un...
Anisotropic core–shell ceramic nanofibrous membrane with improved optical reflectivity and thermal insulation for high-energy laser protection
Abstract The development of multifunctionally coupled materials that can adapt to complex thermophotonic environments is increasingly critical for next-generation aerospace, defense,...
Acute rapamycin treatment reveals distinct mechanisms of dysfunction in a maternal inflammation mouse model
Abstract Maternal inflammatory response (MIR) during early mouse gestation induces a cascade of physiological and behavioral changes associated with autism spectrum disorder (ASD). W...
Versatile electronic phases enabled by intertwined multiple frustrations in an antiferromagnetic two-dimensional semimetal
Abstract Following the discovery of graphene, van der Waals materials have become a major platform for quantum matter, yet strongly interacting phases beyond gra...
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Abstract Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion, and division. Th...
Author Correction: Contextual gating of whisker-evoked responses by frontal cortex supports flexible decision making
VN1K is a pangenome-informed multi-omics and phenomics resource for the Vietnamese population
AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models
Abstract Optimizing murine models for studying Metabolic Dysfunction-Associated Steatohepatitis (MASH) and fibrosis is crucial for understanding disease mechanisms and evaluating the...
Emerging capitalism and sociocultural niche construction in early modern Greece
Abstract Sociocultural niche construction is a key mechanism behind the current planetary crisis. Its causal drivers in past societies remain poorly understood d...
Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy
Adult-to-infant unidirectional neural coupling mediates selective social learning in infants from the United Kingdom and Singapore
Non-local synchronization of continuous time crystals in a semiconductor
Abstract Synchronization resulting in unified collective behavior of the individual elements of a system that are weakly coupled to each other has long fascinate...
The deubiquitinase USP4 stabilizes the SCFFBXO24 ubiquitin E3 ligase to regulate immunity in experimental pneumonia
Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity
Abstract Peptide-activated G protein-coupled receptors (GPCRs) play crucial roles in numerous diseases, but remain difficult therapeutic targets due to the chall...
Supramolecular nanofiber stabilization of microdroplets enables ultra-sensitive virus infection analysis
Comprehensive biophysical and structural profiling of alpha-actinin-2 variants reveals mechanistic diversity in hypertrophic cardiomyopathy
Abstract Hypertrophic cardiomyopathy (HCM) is a genetic disease associated with sudden cardiac death. Variants in alpha-actinin-2 (ACTN2), a Z-disc protein that anchors actin thin fi...