Nature Communications
Articles in this Issue
A Rahman Syndrome mutation in histone H1.4 disrupts chromatin compaction and phase separation
Abstract Rahman syndrome is a rare developmental disorder caused by frameshift mutations in linker histone H1.4 that produce a truncated carboxy-terminal domain with reduced positive...
Initial leukemic epigenomic state determines hypomethylating agent response
Chaperone-mediated autophagy is required for regulatory T cell function
Coulombic control of charge transfer in radicals with quartet recycling luminescence
Abstract Excitons in organic materials are emerging as an attractive platform for tunable quantum technologies. Structures with near-degenerate doublet and tripl...
Anomalous quantized nonlinear soliton pumping
Operando X-ray scattering reveals ordering-mediated solidification in additive manufacturing
Neofunctionalization underlies the evolutionary origin of sclareol biosynthesis in the mint family
Abstract Plant specialized metabolites play essential ecological roles, yet the mechanisms underlying their diversification remain poorly understood. Here, we in...
Strongly-coordinating organoborates with eccentric solvation structure enable secondary calcium metal battery
Dual-channel optogenetics in yeast for multiplexed light-based control of cellular processes and pathways
Abstract Optogenetics which involves the use of light to control cell functions on a genetic level has found utility in studying cell physiology, biomaterials an...
DepoCatalog: mapping diversity of 129 recombinantly produced Klebsiella phage depolymerases
Abstract Our understanding of how depolymerase sequence and structure determine substrate specificity is fragmentary due to the limited number of experimentally...
Author Correction: Kriging-based surrogate data-enriching artificial neural network prediction of strength and permeability of permeable cement-stabilized base
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH
Amino acid-based biological age clock and its implications for human health and aging
Dual-domain metamaterials co-integrated with a compact ultrasonic transducer for highly directional audio generation
SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children
Abstract Mucosal immunity is an important correlate of protection against respiratory infections such as SARS-CoV-2. Comparing B cell responses to vaccines and i...
Triple-interlocked-nanotwinned bulk magnesium alloys with exceptional strength and ageing resistance
Abstract Nanoscale twin boundaries (TBs) effectively restrict the free motion of dislocations by intersecting with other TBs to realize high strength. However, the dislocations paral...
PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized proteins
Abstract Building a universal biochemical constructor, an autonomously self-replicating biochemical system, remains a challenge in synthetic biology. The PURE cell-free system is a s...
GABAergic projections from the suprachiasmatic nucleus to the preoptic area regulate the timing of torpor in mice
Manganese enhances macrophage bactericidal activity in mice with Staphylococcus aureus osteomyelitis via Sirt3-mitophagy axis
Iron overload in the tumor microenvironment induces CD8+ T cell ferroptosis and dysfunction
Abstract While iron homeostasis in cancer cells is well-established, its role in mediating crosstalk between tumors and CD8 +...
Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk
Abstract Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) are two types of clonal hematopoiesis (CH) associated with hematological par...