Initial leukemic epigenomic state determines hypomethylating agent response

Aparna Gopal; Derek Tam; Franziska Mey; Diana Lin; Christina May; Jihong Jiang; Joshua Bridgers; Brett Caswell; Kieran O’Neill; Frederick S. Vizeacoumar; Mackenzie MacAuley; Emilie Haniak; Charles Craddock; Paresh Vyas; Luca Malcovati; Rena Buckstein; Michelle Moksa; Martin Hirst; Franco J. Vizeacoumar; Nadia Medvedev; Michael Heuser; Ryan J. Stubbins; Yu Deng; Aly Karsan

doi:10.1038/s41467-026-73334-3

Initial leukemic epigenomic state determines hypomethylating agent response

A Aparna Gopal D Derek Tam F Franziska Mey D Diana Lin C Christina May J Jihong Jiang J Joshua Bridgers B Brett Caswell K Kieran O’Neill F Frederick S. Vizeacoumar M Mackenzie MacAuley E Emilie Haniak C Charles Craddock P Paresh Vyas L Luca Malcovati R Rena Buckstein M Michelle Moksa M Martin Hirst F Franco J. Vizeacoumar N Nadia Medvedev M Michael Heuser R Ryan J. Stubbins Y Yu Deng A Aly Karsan

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published May 22, 2026

DOI 10.1038/s41467-026-73334-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (24)

A

Aparna Gopal

D

Derek Tam

F

Franziska Mey

D

Diana Lin

C

Christina May

J

Jihong Jiang

J

Joshua Bridgers

B

Brett Caswell

K

Kieran O’Neill

F

Frederick S. Vizeacoumar

M

Mackenzie MacAuley

E

Emilie Haniak

C

Charles Craddock

P

Paresh Vyas

L

Luca Malcovati

R

Rena Buckstein

M

Michelle Moksa

M

Martin Hirst

F

Franco J. Vizeacoumar

N

Nadia Medvedev

M

Michael Heuser

R

Ryan J. Stubbins

Y

Yu Deng

A

Aly Karsan

Initial leukemic epigenomic state determines hypomethylating agent response

Article Details

Journal Info

Authors (24)

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