Nature Communications

High energy triplet-state manipulation via temperature-responsive twisted hetero-annulation systems

Guigui Ye, Yan Gao, Wentao Yuan et al. May 25, 2026 10.1038/s41467-026-73715-8

Abstract Precisely controlling excited-state transitions is vital for advanced technologies, particularly for sensitive, long-lived triplet states. Unlike tradit...

An HDAC4-specific PROTAC degrader achieves radiation sensitization by enhancing ferroptosis in lung cancer

Chun Cheng, Longhua Sun, Jiaxue Yang et al. May 25, 2026 10.1038/s41467-026-73682-0

Pembrolizumab plus high-dose IL-2 in advanced clear cell renal cell carcinoma: six-year survival outcomes and molecular signatures from a phase 2 trial

Jeffrey S. Johnson, Justin W. Miller, Firas Hatoum et al. May 25, 2026 10.1038/s41467-026-73336-1

Reconstructing calcium conductance in MCUb illuminates its molecular design for tuning the mitochondrial calcium uniporter

I-Chi Lee, Po-Hsuan Lai, Chen-Wei Tsai et al. May 25, 2026 10.1038/s41467-026-73711-y

Genome-wide meta-analysis identifies genetic drivers of bile acid metabolism in intrahepatic cholestasis of pregnancy

Jaakko S. Tyrmi, Juha Karjalainen, Samvida S. Venkatesh et al. May 25, 2026 10.1038/s41467-026-73122-z

Regional variations in emergency care vulnerability to summer heat

Wenhua Yu, Rongbin Xu, Wenzhong Huang et al. May 25, 2026 10.1038/s41467-026-73338-z

MiTo: tracing the phenotypic evolution of somatic cell lineages via mitochondrial single-cell multi-omics

Andrea Cossa, Alberto Dalmasso, Guido Campani et al. May 25, 2026 10.1038/s41467-026-71607-5

Diversification in ANME-1 archaea is associated with the presence of highly variable genomic hotspots

Ying-Li Zhou, Jing-Chun Feng, Rui Lu et al. May 25, 2026 10.1038/s41467-026-73573-4

Phenome-wide analysis of downstream health outcomes following second-line antidiabetic agent prescriptions in All of Us

Maxwell Salvatore, Bingyu Zhang, Huilin Tang et al. May 25, 2026 10.1038/s41467-026-72947-y

SOFisher: reinforcement learning-guided experiment designs for spatial omics

Zhuo Li, Weiran Wu, Chuangyi Han et al. May 25, 2026 10.1038/s41467-026-73404-6

Ultra-broadband wireless rectification and frequency mixing via the nonlinear Hall effect in TaIrTe4

Fanrui Hu, Jiayu Lei, Shishun Zhao et al. May 25, 2026 10.1038/s41467-026-73394-5

Machine learning model-guided selective use of temporary diverting ileostomy in rectal cancer surgery: a randomized controlled trial

Shengli Shao, Yanqi Li, Jianghao Li et al. May 25, 2026 10.1038/s41467-026-73565-4

HBV HBx protein masks epigenetic reader Spindlin1 via an inter-molecular zinc finger to subvert transcriptional control

Alexis Clavier, Toshinobu Shida, Maxim A. Droemer et al. May 25, 2026 10.1038/s41467-026-72986-5

De novo design of DNA origami with a generative diffusion model

Chien Truong-Quoc, Kyounghwa Jeon, Jinho Kim et al. May 25, 2026 10.1038/s41467-026-73578-z

Evolution of intragranular pores in potassium niobate ceramics during sintering

Xian-Xian Cai, Zhaonian Zhou, Yeming Huang et al. May 25, 2026 10.1038/s41467-026-73315-6

A highly sensitive genetically encoded red cAMP sensor for multiplex imaging in vivo

Liang Wang, Lingling Li, Xuelin Li et al. May 25, 2026 10.1038/s41467-026-73138-5

Dynamics of dislocation formations and their impacts on exsolution in Ru-doped perovskite oxide

Sungwook Choi, Younghwan Lim, Puspendu Guha et al. May 25, 2026 10.1038/s41467-026-73457-7

Cold sintering of hybrid copper-iodides in transparent ceramics using dolomitization-inspired densification

Yu Ren, Fu-Zhi Dai, Sijia Lu et al. May 25, 2026 10.1038/s41467-026-73625-9

Monolithic integration of p- and n-type doped 2D WSe2 for wafer-scale complementary logic circuits

Yan Hu, Shicheng Zeng, Yi Wang et al. May 25, 2026 10.1038/s41467-026-73144-7

Long-read deep sequencing reveals high rates of multilineage transmission and rapid viral population changes in acute HIV infection

James I. Mullins, Wenjie Deng, Elena E. Giorgi et al. May 25, 2026 10.1038/s41467-026-73496-0

Abstract Understanding the selective forces acting upon HIV early in infection is crucial to design prevention strategies. By leveraging deep sequencing and the short diagnostic inte...

Mast cells support lung eosinophil homeostasis and the acute innate immune response to respiratory syncytial virus

Roopa Hebbandi Nanjundappa, Christopher R. Liwski, Alexander Edgar et al. May 24, 2026 10.1038/s41467-026-73438-w

Abstract As tissue-resident immune cells, mast cells release inflammatory agents in response to local viral infections. Here, we analyze Cpa3...

Dairy cows infected with influenza A(H5N1) reveals low infectious dose and transmission barriers

Carolyn Lee, Natalie N. Tarbuck, Hannah J. Cochran et al. May 24, 2026 10.1038/s41467-026-73490-6

Solar-driven peroxyacid group activation enables＞ 500 h stable hydroxyl-radical defluorination of industrial perfluorophenol wastewater

Yunning Chen, Qixin Zhou, Yan Guo et al. May 24, 2026 10.1038/s41467-026-73548-5

Combined biosynthesis and site-specific incorporation of phenylalanine derivatives from aryl aldehydes or carboxylic acids

Shelby R. Anderson, Abigail P. Spangler, Amanda M. Forti et al. May 23, 2026 10.1038/s41467-026-73618-8

Cryo-EM Structure of the TRPC1/5 Heteromer Enables Design of Antidepressant and Anxiolytic Drug with Reduced Side Effects

Yixiang Chen, Tong Che, Xinyu Cheng et al. May 23, 2026 10.1038/s41467-026-73409-1

Abstract The TRPC1/5 heteromer exhibits electrophysiological and ligand-binding properties distinct from TRPC5 homomers, enabling tissue-specific cellular regulation. Here we present...

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