Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy

J Jiansong Huang J Jing Zhou (Zhejiang Institute of Photoelectronics) X Xiao Liu X Xiaoxu Liu Y Ye Xiao K Kai Li C Chenbo Ding X Xuemin Cai W Wenli Mao C Changfen Xu Y Yuxin Kong Y Yu Deng X Xiaohan Song M Mei Yang (College of Chemistry) D Daohai Du (State Key Laboratory of Drug Research) S Siqi Guo K Kaixian Chen (State Key Laboratory of Drug Research) C Cheng Luo (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine) C Chengqi Yi S Shijie Chen (Innovation Center for AI and Drug Discovery, School of Pharmacy) H Hua-Bing Li

Article Details

Volume / Issue Vol. 17, Issue 1
Published July 22, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (21)

J

Jiansong Huang

J

Jing Zhou

Zhejiang Institute of Photoelectronics

X

Xiao Liu

X

Xiaoxu Liu

Y

Ye Xiao

K

Kai Li

C

Chenbo Ding

X

Xuemin Cai

W

Wenli Mao

C

Changfen Xu

Y

Yuxin Kong

Y

Yu Deng

X

Xiaohan Song

M

Mei Yang

College of Chemistry

D

Daohai Du

State Key Laboratory of Drug Research

S

Siqi Guo

K

Kaixian Chen

State Key Laboratory of Drug Research

C

Cheng Luo

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine

C

Chengqi Yi

S

Shijie Chen

Innovation Center for AI and Drug Discovery, School of Pharmacy

H

Hua-Bing Li