Nature Communications
Articles in this Issue
iSCORE-PD: an isogenic stem cell collection to research Parkinson’s disease
Abstract Genome-edited human pluripotent stem cells (hPSCs) provide a powerful platform to study complex diseases such as Parkinson’s disease (PD). Here, we desc...
Efficient preservation of old methane-derived organic carbon in deep-sea surface sediments
Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone
Abstract Epithelia likely predate the last common animal ancestor, yet the evolutionary origin and nutritional regulation of epithelial remodelling remain poorly...
Non-invasive in vivo acoustoelectric neuromodulation and its contribution to ultrasound stimulation
Abstract Non-invasive brain stimulation offers therapeutic potential without surgery, yet existing electrical approaches lack spatial precision due to the long wavelengths of electri...
Sequence redesign of glycosyltransferases for enhanced heterologous expression and glycosylation efficiency in Escherichia coli
Molecular diffusion enhanced performance evaluation of metal-organic frameworks for CO2 capture
Abstract Molecular diffusion is a fundamental property that limits the performance of solid sorbents in carbon dioxide capture and separation applications. Unique to each sorbent, ga...
Transfer-printed yellow and red InGaN micro-LEDs on diamond for ultra-low-power high-speed optical interconnects
Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities
Reverse engineering of BNIP3 identifies a mitochondrial protective peptide
Abstract Recent advances in mitochondrial network dynamic and signalling highlight mitochondria as key therapeutic targets across diverse diseases. Yet, high drug development failure...
Probing non-ergodicity and symmetry via direct measurement of coherent scattering in a shaken rotor
A translational approach to airway reconstruction leveraging decellularized meniscus and cartilage progenitor cells
Intermediate accumulated upon interruption of fatty acid oxidation flux promotes tumoral ferroptosis and improves immunotherapy
Guide RNA reprogramming facilitates minimized tracrRNA-dependent off-target and versatile CRISPR/Cas9 engineering
The confounding effects of skin colour in photoacoustic imaging
Abstract Skin colour is known to confound optical devices, adversely impacting care for patients with darker skin. Photoacoustic imaging (PAI) combines optics and ultrasound for deep...
Cortical and white matter myelination proceed in concert during early infancy
Abstract The infant brain undergoes rapid myelination that is critical for healthy brain function. This development has been characterized for gray and white matter independently, bu...
Inequality in human development amplifies climate-related disaster risk
Abstract The impacts of climate-related disasters are shaped by the interaction between hazard intensity, exposure, and vulnerability. However, the influence of hazard intensity and...
15-LOX-catalytic bias towards ether-(alkenyl)-ETE-PEs oxidation bestows selectivity of PRO-ferroptotic cell death signaling
Abstract Ether (alkyl/alkenyl) phospholipids, particularly phosphatidylethanolamine (PE) and phosphatidylcholine (PC), are broadly represented in membranes, but...
Dynamic hydroxyl mediated charge buffering stabilizes high valence ruthenium edge sites for acidic water oxidation
Plug-and-play – enzymatic amino acid production from methanol and carbon dioxide
Abstract Amino acids are the building blocks of proteins and thus among the macronutrients to feed humankind. They have extensive industrial applications as anim...
Room-temperature ferroelectricity in NaNbO3 membrane
Resolving intrinsic dislocation structure in perovskite crystals using pulsed electron beam with atomic resolution
Redox-regulated in situ-forming hydrogel informed by single-cell transcriptomics for functional restoration of injured vocal folds
Pulsed-electron illumination does not reduce beam damage for imaging biological macromolecules
Abstract Radiation damage remains a fundamental limitation in cryo-electron microscopy (cryo-EM), constraining the total electron dose that can be used and thus...
Engineering a robust and autonomous biological funneling for efficient valorization of lignin-related aromatics
Abstract Lignin-related aromatics are promising renewable feedstocks, but their microbial conversion into useful compounds is fundamentally constrained by substr...
Structure of core assembly of the Clostridioides difficile germinosome
Abstract The germinosome is the machinery of Clostridioides difficile that sets in motion the process of spore germinatio...