Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities

Itziar Uriarte-Arrazola; Míriam Magallón-Lorenz; Juana Fernández-Rodríguez; Jiajing Zhang; Emily Lee; Sara Ortega-Bertran; Edgar Creus-Bachiller; Judit Farrés-Casas; Kelli M. Wilson; Crystal McKnight; Katlin Recabo; Ignacio Blanco; Héctor Salvador; Cleofé Romagosa; Conxi Lázaro; Helena Mazuelas; Bernat Gel; Marc Ferrer; Meritxell Carrió; Eduard Serra

doi:10.1038/s41467-026-73119-8

Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities

I Itziar Uriarte-Arrazola M Míriam Magallón-Lorenz J Juana Fernández-Rodríguez J Jiajing Zhang (School of Chemistry and Chemical Engineering, National Special Superfine Powder Engineering Research Center) E Emily Lee S Sara Ortega-Bertran E Edgar Creus-Bachiller J Judit Farrés-Casas K Kelli M. Wilson C Crystal McKnight K Katlin Recabo I Ignacio Blanco H Héctor Salvador C Cleofé Romagosa C Conxi Lázaro H Helena Mazuelas B Bernat Gel M Marc Ferrer M Meritxell Carrió E Eduard Serra

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published June 17, 2026

DOI 10.1038/s41467-026-73119-8

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

I

Itziar Uriarte-Arrazola

M

Míriam Magallón-Lorenz

J

Juana Fernández-Rodríguez

J

Jiajing Zhang

School of Chemistry and Chemical Engineering, National Special Superfine Powder Engineering Research Center

E

Emily Lee

S

Sara Ortega-Bertran

E

Edgar Creus-Bachiller

J

Judit Farrés-Casas

K

Kelli M. Wilson

C

Crystal McKnight

K

Katlin Recabo

I

Ignacio Blanco

H

Héctor Salvador

C

Cleofé Romagosa

C

Conxi Lázaro

H

Helena Mazuelas

B

Bernat Gel

M

Marc Ferrer

M

Meritxell Carrió

E

Eduard Serra

Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities

Article Details

Journal Info

Authors (20)

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