Nature Communications
Articles in this Issue
Twist-stacked black phosphorus for wide-spectral chiral photodetection
Global risk pooling mitigates financial risk from drought in hydropower-dependent countries
Abstract More than 50 countries rely on hydropower for over 25% of their electricity generation, making them vulnerable to drought and resulting revenue losses. Governments can offse...
Spin-state engineering of single titanium adsorbates on ultrathin magnesium oxide
Near-infrared light-driven nanomotors-based microneedles for the active therapy of bacterial infected acne
Glutamatergic projection neurons in the basal forebrain underlie learned olfactory associational valence assignments
Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data
Abstract Spatial transcriptomics (ST) links tissue morphology with gene expression values, opening new avenues for digital pathology. Deep learning models are used to predict gene ex...
DNA end configurations dictate synaptic complex formation during NHEJ-mediated end bridging
Cascading chirality from molecule to twisted microstructures with amplified circularly polarized luminescence
Advances, challenges and prospects of origami and kirigami optoelectronics
Identification of thermotolerant non-canonical PAMs for robust one-pot CRISPR-Cas12a detection
Abstract The canonical PAM site TTTV (where V = A, G, or C) is widely used in the design of CRISPR-Cas12a systems for both genome editing and diagnostic applicat...
NALIRIFOX versus gemcitabine plus nab-paclitaxel in Chinese patients with advanced pancreatic adenocarcinoma: a randomized, open-label phase II trial
Spatiotemporally controlled drug release via a click-release system utilizing mono-alkyl-hydroxylamine and cyclooctyne chemistry
Endothelial FUNDC1 regulates metabolic reprogramming and the obesity-diabetes transition through the SIRT3/GATA2/endothelin-1 axis
Estimating COVID-19 incidence and prevalence using lateral flow tests in England and Scotland, 2023-2024
Abstract SARS-CoV-2 continues to cause substantial morbidity and mortality, particularly in winter. During the SARS-CoV-2 pandemic, community prevalence surveys...
Molecular basis of antagonism of the dimeric human arginine vasopressin receptor 1A
Deciphering stress perturbations throughout the 2025 Mw 7.1 Dingri, Southern Xizang Earthquake
Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy
An artificial cell capable of signal transduction mediated by ADRB2 for the regulation of glycogenolysis
Abstract Bottom-up construction of artificial cells helps elucidate the working mechanism of cells. Signal transduction from extracellular to intracellular artificial cells is essent...
Epoxy-oxylipins direct monocyte fate in inflammatory resolution in humans
Abstract The role of cytochrome P450-derived epoxy-oxylipins and their metabolites in human inflammation and resolution is unknown. We report that epoxy-oxylipin...
Tissue-specific and sex-biased glycoproteomic landscape of Schistosoma mansoni
Unveiling the metallogenic continuum of an Archean craton
Reentrant melting of scarred odd crystals by self-shear
Abstract Spatial confinement can induce geometrical frustration in condensed phases, giving rise to topological defects that confer materials with new and exotic properties. Here, we...
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate
Adipocytic sclerostin loop3-LRP4 interaction required by sclerostin to impair whole-body lipid and glucose metabolism
Abstract Sclerostin, which has three loops, inhibits bone formation and impairs whole-body lipid and glucose metabolism. The marketed therapeutic sclerostin antibody for postmenopaus...