Nature Communications
Articles in this Issue
ProteoAutoNet: high-throughput co-eluted protein analysis with robotics and machine learning
Abstract Co-fractionation mass spectrometry (CF-MS) enables large-scale profiling of endogenous protein-protein interactions, yet CF-MS data generation is of low throughput and there...
Comparative multi-omic analysis reveals conserved and derived mechanisms of fin and limb regeneration
Abstract Comparative studies of vertebrate appendages offer a powerful framework for uncovering shared components of an ancestral regeneration toolkit. Here, we...
Glass formation in hybrid metal halides via breaking molecular rotational order
Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers
A Magnon-photon interface based on Van der Waals Magnetic semiconductor
Uncovering the molecular logic of cortical wiring between neuronal subtypes across development through ligand–receptor inference
Ultrathin liquid cells for microsecond time-resolved cryo-EM
Abstract Microsecond time-resolved cryo-electron microscopy promises to significantly advance our understanding of protein function by rendering cryo-electron microscopy (cryo-EM) fa...
Plastic mulch productivity-sustainability tradeoffs and pathways toward an eco-friendly framework: insights from a global meta-analysis
Reversible bismuth reduction-driven dark photoelectrochemistry
CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
Dynamic single-cell transcriptomics reveals lsamp-guided neural network formation in male S. japonicum driving female reproduction
Resurrected nitrogenases recapitulate canonical N-isotope biosignatures over two billion years
Camouflaged nanorobots target and regulate macrophage subcellular organelle crosstalk patterns to promote neural regeneration
A common DNA deletion altering the 3’UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients
Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release
Abstract The type VI secretion system (T6SS) is a dynamic protein nanomachine found in Gram-negative bacteria that secretes toxic effectors into prey-cells. For secretion, effectors...
Atypical pericapillary Ly6G⁺Nur77⁺ macrophages initiate type-2 immune responses to allergens in the mouse lung
Abstract The mechanisms of airway allergen sensing and type 2 immune response initiation remain poorly understood. Using a mouse house dust mite (HDM)-induced al...
Asymmetrical covalent organic framework mixed matrix membranes for highly efficient gas separation
The simplest iminophosphane HPNH and its photoisomerization to aminophosphinidene H2NP
Assimilative causal inference
Hierarchical maturation of structural brain connectomes from birth to childhood
Harnessing Van Hove singularities for terahertz photoresponse via Fermi surface reconstruction in kagome lattices
Silencing lipid catabolism determines longevity in response to fasting
Abstract Oscillations between lipid anabolism and catabolism are essential for maintaining cellular health during metabolic fluctuations. Fasting, a conserved de...
Dynamic signature of activity-stability tradeoff in lactamase evolution
Abstract Our ability to understand protein evolution hinges on understanding how evolutionary landscapes are shaped at the fundamental protein level. Using TEM-1 β-lactamase we show...