Nature Communications
Articles in this Issue
Decoding efficacy and resistance space at a drug binding site
Abstract Assessing and understanding the impacts of all possible mutations at a drug binding site remain challenging. Here we use multiplex oligo targeting for m...
Sensory encoding and memory retrieval are coordinated with propagating waves in the human brain
Deep learning drives autonomous molecular reactions with single-bond selectivity in tetra-brominated porphyrins on Au(111)
Local alkalinity enables high-performance pure water anion exchange membrane electrolysis
Molecular clustering unlocks high-performance hydrovoltaics across temperatures from −35 °C to 80 °C
Enhancing CAR- and TCR-mediated targeting of cancer via an immune synapse-stabilizing receptor
Short-range order in high entropy carbides
Abstract High-entropy carbides (HECs) are a new class of materials with properties that are promising for applications in extreme environments, involving high temperature, corrosion,...
Interfacial dipole engineering by self-assembled molecules in n-i-p and p-i-n perovskite solar cells
Regulating interfacial water for oxygen transfer to benzylic C(sp3)–H bonds via Ni-activated tungsten-oxygen covalency
Machine learning for microscopy data analytics targeting real-time optical characterization of semiconductor nanocrystals
Abstract Semiconductor nanocrystals with uniform morphology and composition are expected to show consistent responses during light-matter interactions. However, microscopy reveals si...
High quality-factor terahertz phonon-polaritons in layered lead iodide
Bell correlations between momentum-entangled pairs of 4He* atoms
Can ferric-oxyl excited states explain elongated iron-oxygen bonds in heme peroxidase catalytic intermediates?
Abstract The use of X-ray structures to determine and interpret the ferryl iron-oxygen bond order in molecular oxygen-activating heme enzymes has, in the past, b...
Molecular mechanism of phosphate import by the bacterial PstSCAB transporter
Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
Metabolic characterization of tumor-immune interactions by multiplexed immunofluorescence reveals spatial mechanisms of immunotherapy response in non-small cell lung carcinoma (NSCLC)
Abstract Immune checkpoint inhibitors (ICI) have improved clinical outcomes for some patients with advanced NSCLC, however a substantial proportion of patients remain treatment resis...
HCMV infection disrupts barrier functions and promotes epithelial–mesenchymal transition in a cholangiocyte organoid model
Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer’s disease-like pathology in mice
Cracking the code of multi-layer films to promote circularity in single-use plastic packaging
Altered B cell activation contributes to the immunopathogenesis of childhood arthritis-associated uveitis
Abstract In Juvenile Idiopathic Arthritis (JIA), the most common childhood rheumatic disease, many patients also develop uveitis (JIA-uveitis), risking life-long...
Multifunctional lithium niobate platform for photodetection and photoacoustic and thermoelastic gas sensing
Abstract Leveraging the intrinsic multi physics nature of ferroelectric lithium niobate, we present a multi-functional platform (LN-MFP) that seamlessly integrates photoacoustic spec...
Hierarchical assembly of a Ti24 metal-organic polyhedron via kinetic trapping of intermediates
A microphysiological human mini-bladder reveals urine-urothelium interplay in tissue resilience and UPEC recurrence in urinary tract infections
Abstract Urine is a dynamic and highly variable biofluid. Urine-urothelium interactions are a critical yet underexplored factor in bladder homoeostasis and urina...